Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.
Biomarker and diagnostic research for diabetic neuropathy has been reported in the published literature.
44 clinical trials registered, 15 recruiting. Interventions under study include other interventions, drug therapy, medical devices, and procedural interventions. Pipeline includes 2 PHASE4, 2 PHASE3, 4 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT06201611](https://clinicaltrials.gov/study/NCT06201611) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:49 AM UTC
Evaluating a Nitric Oxide Generator, Nebivolol as a Disease Modifier in Patients With Diabetic Neuropathy. |
PHASE2 |
St. John's Research Institute |
RECRUITING |
[NCT04678895](https://clinicaltrials.gov/study/NCT04678895) | Low-Dose Naltrexone for the Treatment of Painful Diabetic Neuropathy | PHASE2 | Dartmouth-Hitchcock Medical Center | RECRUITING |
[NCT06958302](https://clinicaltrials.gov/study/NCT06958302) | The Relation Between Diabetic Neuropathy and Muscle Mass in Type 2 Diabetes Mellitus Patients | — | Ain Shams University | RECRUITING |
[NCT06668623](https://clinicaltrials.gov/study/NCT06668623) | Effect of Reiki on Neuropathic Pain Severity and Sleep Quality in Patients With Diabetic Neuropathy | NA | TC Erciyes University | RECRUITING |
[NCT06452914](https://clinicaltrials.gov/study/NCT06452914) | Clinical Outcomes Related to Treatment of Distal Symmetric Polyneuropathy Using Semiconductor Embedded Therapeutic Socks | NA | Endocrine Research Solutions | RECRUITING |
200 publications have been identified in PubMed for diabetic neuropathy. Research spans Review / Meta-Analysis (42%), Basic Science / Preclinical (27%), and Epidemiology / Natural History (13%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 83 | 42% |
Laboratory research | 53 | 27% |
Disease patterns and progression | 26 | 13% |
Clinical study results | 15 | 8% |
New treatment approaches | 11 | 6% |
Testing and diagnosis research | 5 | 3% |
Other research | 4 | 2% |
Patient case studies | 1 | 1% |
Zamponi V (2026). [PMID: 41753308](https://pubmed.ncbi.nlm.nih.gov/41753308/). *J Clin Med*. [Review / Meta-Analysis]
Burhan A (2026). [PMID: 41534596](https://pubmed.ncbi.nlm.nih.gov/41534596/). *Diabetes Res Clin Pract*. [Review / Meta-Analysis]
Eldesouky O (2026). [PMID: 41494160](https://pubmed.ncbi.nlm.nih.gov/41494160/). *Pain*. [Basic Science / Preclinical]
Milbourn VEL (2026). [PMID: 41827410](https://pubmed.ncbi.nlm.nih.gov/41827410/). *J Clin Med*. [Review / Meta-Analysis]
Singh DD (2026). [PMID: 40993953](https://pubmed.ncbi.nlm.nih.gov/40993953/). *Curr Diabetes Rev*. [Review / Meta-Analysis]
Wei J (2026). [PMID: 41933993](https://pubmed.ncbi.nlm.nih.gov/41933993/). *Trends Mol Med*. [Review / Meta-Analysis]
Rajput JPS (2026). [PMID: 41788111](https://pubmed.ncbi.nlm.nih.gov/41788111/). *Cureus*. [Review / Meta-Analysis]
Sun W (2026). [PMID: 42112353](https://pubmed.ncbi.nlm.nih.gov/42112353/). *Front Immunol*. [Review / Meta-Analysis]
Li J (2026). [PMID: 42125665](https://pubmed.ncbi.nlm.nih.gov/42125665/). *Front Immunol*. [Basic Science / Preclinical]
Jiang S (2026). [PMID: 41609860](https://pubmed.ncbi.nlm.nih.gov/41609860/). *Journal of neurology*. [Review / Meta-Analysis]
AI-curated news mentioning diabetic neuropathy
Updated Jan 7, 2026
Researchers at NIH show that transferring healthy mitochondria from glial cells to nerve cells can potentially reduce nerve pain and degeneration associated with diabetic and chemotherapy-induced neuropathy. This breakthrough could lead to new therapeutic strategies for managing nerve-related pain.