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Duplication of the urethra is a rare congenital genitourinary anomaly, encompassing a wide spectrum of anatomic variants in which the urethra is partially or totally duplicated, which may be asymptomatic or cause symptoms such as incontinence, recurrent urinary infections and difficulty urinating.
Features include common findings: Epispadias, Hypospadias, Vesicoureteral reflux, and Anorectal anomaly; and sometimes findings: Recurrent urinary tract infections, Urinary incontinence, Chordee, and Bifid scrotum and others.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Kidneys and urinary system | 4 | Recurrent urinary tract infections, Urinary incontinence, Urinary bladder wall hypertrophy |
Phenotype severity distribution: 4 common features.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for duplication of urethra.
22 publications have been identified in PubMed for duplication of urethra. Research spans Case Report / Case Series (95%) and Other (5%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 21 | 95% |
Other research |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:55 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Blood and immune system |
1 |
Recurrent urinary tract infections |
Digestive system | 1 | Gastroschisis |
Brain and nerves | 1 | Pain |
1 |
5% |
Ashbrook CQ (2026). [PMID: 42241731](https://pubmed.ncbi.nlm.nih.gov/42241731/). *J Pediatr Urol*. [Case Report / Case Series]
Ueda N (2026). [PMID: 41947939](https://pubmed.ncbi.nlm.nih.gov/41947939/). *IJU Case Rep*. [Case Report / Case Series]
Lerendegui L (2026). [PMID: 40940001](https://pubmed.ncbi.nlm.nih.gov/40940001/). *Urology*. [Case Report / Case Series]
Sumayya H (2026). [PMID: 42064654](https://pubmed.ncbi.nlm.nih.gov/42064654/). *J Indian Assoc Pediatr Surg*. [Case Report / Case Series]
Diallo TMO (2026). [PMID: 42005290](https://pubmed.ncbi.nlm.nih.gov/42005290/). *Urol Case Rep*. [Case Report / Case Series]
Jordan Balladares RE (2026). [PMID: 42137565](https://pubmed.ncbi.nlm.nih.gov/42137565/). *Front Pediatr*. [Case Report / Case Series]
Bal A (2026). [PMID: 42103336](https://pubmed.ncbi.nlm.nih.gov/42103336/). *BMJ Case Rep*. [Case Report / Case Series]
Saju PR (2025). [PMID: 40735164](https://pubmed.ncbi.nlm.nih.gov/40735164/). *Urol Case Rep*. [Case Report / Case Series]
Alemu CT (2025). [PMID: 40186157](https://pubmed.ncbi.nlm.nih.gov/40186157/). *BMC Urol*. [Case Report / Case Series]
Cherkaoui Jaouad MR (2025). [PMID: 40496083](https://pubmed.ncbi.nlm.nih.gov/40496083/). *Radiol Case Rep*. [Case Report / Case Series]