Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Dysplasia epiphysealis hemimelica (DEH), or Trevor's disease, is a rare condition that most commonly affects the epiphysis (the end) of long bones in children. Early diagnosis and treatment are necessary to prevent joint dysfunction and deformity and may be surgical or non-surgical depending on the location and the symptoms. Due to the progressive nature of this disorder and the chance of worsening deformity, patients should be followed until skeletal maturity. The cause of dysplasia epiphysealis hemimelica is not known.
Features include: Bone and joint problems (abnormality of the skeletal system) and Overgrowth.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Bones and joints | 1 | Bone and joint problems (abnormality of the skeletal system) |
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for dysplasia epiphysealis hemimelica.
8 publications have been identified in PubMed for dysplasia epiphysealis hemimelica. Research spans Case Report / Case Series (75%) and Review / Meta-Analysis (25%).
Kerwin A (2026). [PMID: 42245421](https://pubmed.ncbi.nlm.nih.gov/42245421/). *J Surg Case Rep*. [Case Report / Case Series]
Kantiwal P (2026). [PMID: 41684982](https://pubmed.ncbi.nlm.nih.gov/41684982/). *Cureus*. [Case Report / Case Series]
Stavropoulos NA (2026). [PMID: 41632888](https://pubmed.ncbi.nlm.nih.gov/41632888/). *SICOT J*. [Case Report / Case Series]
Chen CH (2025). [PMID: 40131113](https://pubmed.ncbi.nlm.nih.gov/40131113/). *Radiology*. [Case Report / Case Series]
Bani Essa S (2025). [PMID: 41364308](https://pubmed.ncbi.nlm.nih.gov/41364308/). *J Am Acad Orthop Surg Glob Res Rev*. [Review / Meta-Analysis]
Artioli E (2024). [PMID: 38435317](https://pubmed.ncbi.nlm.nih.gov/38435317/). *J Orthop*. [Review / Meta-Analysis]
Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 8:43 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Lui TH (2024). [PMID: 39233816](https://pubmed.ncbi.nlm.nih.gov/39233816/). *Arthrosc Tech*. [Case Report / Case Series]
De Pellegrin M (2024). [PMID: 39086380](https://pubmed.ncbi.nlm.nih.gov/39086380/). *Foot Ankle Orthop*. [Case Report / Case Series]
AI-curated news mentioning dysplasia epiphysealis hemimelica
Updated Jun 3, 2026
A case study details a child with recurrent dysplasia epiphysealis hemimelica of the ankle, necessitating three surgical excisions over five years. This highlights the challenges in managing this rare condition and the need for ongoing research.