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dystonia 21 (DYT21) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

dystonia 21

MONDO:0013813

Also known as:DYT21dystonia type 21primary dystonia, DYT21 type

Overview

Primary dystonia, DYT21 type is a subtype of mixed dystonia with a late-onset form of pure torsion dystonia.

GeneticsAutosomal dominant

Clinical Presentation

Features include: Torticollis, Laryngeal dystonia, and Blepharospasm.

Organ System	Phenotype Count	Example Features
Brain and nerves	1	Laryngeal dystonia

Explore clinical features

Diagnosis

Biomarker and diagnostic research for dystonia 21 has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for dystonia 21.

158 publications have been identified in PubMed for dystonia 21. Research spans Epidemiology / Natural History (27%), Review / Meta-Analysis (19%), and Basic Science / Preclinical (18%).

Research Type	Count	% of Total
Disease patterns and progression	42	27%

Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 11:29 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:614588

Orphanet

European rare disease database

Orphanet:306734

GARD

Genetic and Rare Diseases Info Center

GARD:17383

Questions for Your Care Team

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dystonia 21

Overview

Clinical Presentation

Explore clinical features

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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