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Elastoderma is a rare condition that affects the skin. People affected by elastoderma generally have increased laxity of skin covering a specific area of the body. Decreased recoil of the skin has also been reported. Although any part of the body can be affected, the skin of the neck and extremities (arms and legs, especially at the elbows and/or knees) are most commonly involved. The exact underlying cause is currently unknown; however, it generally occurs sporadically in people with no family history of the condition. There is no standard therapy available for elastoderma. Some cases have been treated with surgical excision (removal of affected skin), but hyperlaxity of skin often returns following the surgery.
Features include always present findings: Cutis laxa; and very common findings: Papule, Skin nodule, and Premature skin wrinkling. 7 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Skin | 4 | Papule, Skin nodule, Eczematoid dermatitis |
Phenotype severity distribution: 1 always present feature, 3 very common features, 1 common feature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for elastoderma.
1 publication has been identified in PubMed for elastoderma. Research spans Case Report / Case Series (100%).
Fagan EF (2026). [PMID: 41705451](https://pubmed.ncbi.nlm.nih.gov/41705451/). *Pediatr Dermatol*. [Case Report / Case Series]
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 11:21 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center