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eosinophilic pustular folliculitis (EPF) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

eosinophilic pustular folliculitis

MONDO:0023076

Also known as:EPFOfuji diseaseOfuji's disease

Overview

Eosinophilic pustular folliculitis (EPF) is a skin disorder characterized by recurring itchy, red or skin-colored bumps and pustules (bumps containing pus). The condition is named after the fact that skin biopsies of this disorder find eosinophils (a type of immune cell) around hair follicles. The papules mostly appear on the face, scalp, neck and trunk and may persist for weeks or months. EPF affects males more than females.There are several variants of EPF includingclassic eosinophilic pustular folliculitis (mainly occurring in adults in Japan); HIV-associated EPF, also referred to as immunosuppression-associated EPF; and infantile EPF (with onset from birth or within the first year of life). Whether these are distinct disorders rather than variants of one disorder is controversial, partly because the underlying cause of EFP is not known.Several treatments have been described with variable results, including various oral or topical medications and phototherapy. In patients with HIV-associated disease, antiretroviral therapy tends to greatly diminish symptoms or even eliminate the condition.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for eosinophilic pustular folliculitis.

30 publications have been identified in PubMed for eosinophilic pustular folliculitis. Research spans Case Report / Case Series (66%), Review / Meta-Analysis (21%), and Other (14%).

Research Type	Count	% of Total
Patient case studies	19	66%

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 5:25 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:8534

Questions for Your Care Team

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Kisho

eosinophilic pustular folliculitis

Overview

Research Landscape

Medical References

External Resources

GARD

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Upadacitinib Induces Rapid Remission in Refractory Eosinophilic Pustular Folliculitis with Facial Involvement: Aa Case Report.

eosinophilic pustular folliculitis

Overview

Research Landscape

Medical References

External Resources

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Upadacitinib Induces Rapid Remission in Refractory Eosinophilic Pustular Folliculitis with Facial Involvement: Aa Case Report.