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epidemic louse-borne typhus - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

epidemic louse-borne typhus

MONDO:0019362

Also known as:typhusepidemic typhusepidemic typhus fever

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Overview

A gram-negative bacterial infection caused by Rickettsia prowazekii. It is spread by lice infected with the bacteria. Signs and symptoms include sudden headache, generalized muscle pain, malaise, and macular skin lesions. The infection may affect the central nervous system causing encephalitis.

Clinical Trials3 registered

Diagnosis

Biomarker and diagnostic research for epidemic louse-borne typhus has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

3 clinical trials registered. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE4. Research is primarily sponsored by academic and government institutions.

164 publications have been identified in PubMed for epidemic louse-borne typhus. Research spans Review / Meta-Analysis (30%), Epidemiology / Natural History (27%), and Case Report / Case Series (15%).

Research Type	Count	% of Total
Research summaries	49

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:05 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:83314

GARD

Genetic and Rare Diseases Info Center

GARD:19032

Questions for Your Care Team

→Are any of the 3 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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epidemic louse-borne typhus

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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