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A hypersensitivity pneumonitis caused by the repeated exposure and inhalation of biological dust (such as hay dust, mold spores, or other agricultural products). It is considered a type II hypersensitivity inflammatory reaction. In the acute phase, signs and symptoms include fever, chills, cough, dyspnea, headache, and chest tightness. The subacute phase manifests as chronic cough, dyspnea, anorexia, and weight loss. The chronic phase results from the prolonged exposure to the antigen and is characterized by severe dyspnea and irreversible damage to the lungs.
Biomarker and diagnostic research for farmer's lung disease has been reported in the published literature.
No clinical trials have been registered for farmer's lung disease.
9 publications have been identified in PubMed for farmer's lung disease. Research spans Epidemiology / Natural History (56%), Review / Meta-Analysis (22%), and Diagnostic / Biomarker (11%).
Mahmoud MAM (2025). [PMID: 40128693](https://pubmed.ncbi.nlm.nih.gov/40128693/). *BMC veterinary research*. [Basic Science / Preclinical]
Creswell PD (2025). [PMID: 40020223](https://pubmed.ncbi.nlm.nih.gov/40020223/). *Journal of public health management and practice : JPHMP*. [Epidemiology / Natural History]
Hatim L (2025). [PMID: 40237653](https://pubmed.ncbi.nlm.nih.gov/40237653/). *Chronic respiratory disease*. [Epidemiology / Natural History]
Rouzet A (2025). [PMID: 40578754](https://pubmed.ncbi.nlm.nih.gov/40578754/). *Journal of immunological methods*. [Diagnostic / Biomarker]
Fishwick D (2025). [PMID: 40865983](https://pubmed.ncbi.nlm.nih.gov/40865983/). *Occupational medicine (Oxford, England)*. [Epidemiology / Natural History]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:59 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Hurraß J (2024). [PMID: 38756207](https://pubmed.ncbi.nlm.nih.gov/38756207/). *Allergologie select*. [Review / Meta-Analysis]
Erçen Diken Ö (2024). [PMID: 39169372](https://pubmed.ncbi.nlm.nih.gov/39169372/). *BMC pulmonary medicine*. [Epidemiology / Natural History]
Zhang X (2024). [PMID: 38544315](https://pubmed.ncbi.nlm.nih.gov/38544315/). *International journal of environmental health research*. [Review / Meta-Analysis]
Kuberka Z (2024). [PMID: 38539145](https://pubmed.ncbi.nlm.nih.gov/38539145/). *BMC veterinary research*. [Epidemiology / Natural History]