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Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare and severe form of pityriasis lichenoides et varioliformis acuta (PLEVA). PLEVA is characterized by skin lesions that ulcerate, breakdown, form open sores, then form a red-brown crust. FUMHD often begins as PLEVA, but then rapidly and suddenly progresses to large, destructive ulcers. There may be fever and extensive, painful loss of skin tissue as well as secondary infection of the ulcers. Diagnosis of FUMHD is confirmed by biopsy of skin lesions. FUMHD occurs more frequently in children, peaking at age 5 to 10. Males tend to be affected more often than females. While some cases of FUMHD have resolved without therapy, others have resulted in death. Early diagnosis and prompt treatment may help to reduce morbidity and death.
No clinical trials have been registered for febrile ulceronecrotic Mucha-Habermann disease.
5 publications have been identified in PubMed for febrile ulceronecrotic Mucha-Habermann disease. Research spans Case Report / Case Series (80%) and Review / Meta-Analysis (20%).
Luo J (2026). [PMID: 42109482](https://pubmed.ncbi.nlm.nih.gov/42109482/). *Front Pediatr*. [Case Report / Case Series]
Shen YH (2025). [PMID: 39969860](https://pubmed.ncbi.nlm.nih.gov/39969860/). *JAMA Dermatol*. [Case Report / Case Series]
Milanova-Ilieva D (2025). [PMID: 40560064](https://pubmed.ncbi.nlm.nih.gov/40560064/). *Am J Dermatopathol*. [Review / Meta-Analysis]
Somasundaram A (2024). [PMID: 38234081](https://pubmed.ncbi.nlm.nih.gov/38234081/). *Pediatr Dermatol*. [Case Report / Case Series]
Ma Z (2024). [PMID: 38715678](https://pubmed.ncbi.nlm.nih.gov/38715678/). *Transl Pediatr*. [Case Report / Case Series]
Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 1:52 AM UTC
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Genetic and Rare Diseases Info Center
AI-curated news mentioning febrile ulceronecrotic Mucha-Habermann disease
Updated May 24, 2026
A case report details a fatal pediatric instance of febrile ulceronecrotic Mucha-Habermann disease, highlighting significant diagnostic and therapeutic challenges. This case underscores the complexities involved in managing this rare condition.