Features include always present findings: Stage 5 chronic kidney disease, Microcephaly, Delayed CNS myelination, and Protein in the urine (proteinuria) and others; and common findings: Arachnodactyly, Brain shrinkage (cerebral atrophy), Shrinkage of the cerebellum (cerebellar atrophy), and Low muscle tone (hypotonia) and others.

YRDC function has not been fully characterized.

Galloway-Mowat syndrome 10 is associated with mutations in the YRDC gene on chromosome 1.

Genetic testing for YRDC is available. Testing is considered confirmatory for diagnosis.

Phenotype severity distribution: 6 always present features, 9 common features.

No clinical trials have been registered for Galloway-Mowat syndrome 10.

5 publications have been identified in PubMed for Galloway-Mowat syndrome 10. Research spans Review / Meta-Analysis (40%), Case Report / Case Series (40%), and Basic Science / Preclinical (20%).

Recent Publications

• Wei B (2026). [PMID: 41782252](https://pubmed.ncbi.nlm.nih.gov/41782252/). *Ophthalmic genetics*. [Case Report / Case Series]

• Torra R (2025). [PMID: 40115110](https://pubmed.ncbi.nlm.nih.gov/40115110/). *Clinical kidney journal*. [Review / Meta-Analysis]

• Yari A (2025). [PMID: 39661309](https://pubmed.ncbi.nlm.nih.gov/39661309/). *Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology*. [Case Report / Case Series]

• Huang L (2025). [PMID: 40533795](https://pubmed.ncbi.nlm.nih.gov/40533795/). *Cell communication and signaling : CCS*. [Review / Meta-Analysis]

• Teng H (2024). [PMID: 39063131](https://pubmed.ncbi.nlm.nih.gov/39063131/). *International journal of molecular sciences*. [Basic Science / Preclinical]