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gastric mucosa-associated lymphoid tissue lymphoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

gastric mucosa-associated lymphoid tissue lymphoma

MONDO:0006226

Also known as:MALT lymphoma of stomachMALT lymphoma of the stomachMALToma of stomach

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Overview

A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy.

Clinical Trials5 registered

Diagnosis

Biomarker and diagnostic research for gastric mucosa-associated lymphoid tissue lymphoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

5 clinical trials registered. Interventions under study include drug therapy, other interventions, procedural interventions, and biologic therapy. Pipeline includes 3 PHASE2, 1 EARLY_PHASE1. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT03680586](https://clinicaltrials.gov/study/NCT03680586)

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:32 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 5 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	21	29%
Research summaries	16	22%
Disease patterns and progression	10	14%
Testing and diagnosis research	8	11%
Clinical study results	8	11%
Laboratory research	4	6%
New treatment approaches	4	6%
Other research	1	1%

Kisho

gastric mucosa-associated lymphoid tissue lymphoma

Overview

Diagnosis

Research Landscape

Medical References

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Pulmonary Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue (PMZL-MALT) Diagnosed by Radial Probe Endobronchial Ultrasound-Guided Biopsy: A Case Report.

Double-hit primary high-grade gastric B-cell lymphoma presenting with pancytopaenia and atraumatic back pain: A case report.

gastric mucosa-associated lymphoid tissue lymphoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Pulmonary Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue (PMZL-MALT) Diagnosed by Radial Probe Endobronchial Ultrasound-Guided Biopsy: A Case Report.

Double-hit primary high-grade gastric B-cell lymphoma presenting with pancytopaenia and atraumatic back pain: A case report.