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giant cell glioblastoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

giant cell glioblastoma

MONDO:0016682

Also known as:Monstrocellular sarcomaMonstrocellular sarcoma [obs]

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Overview

A rare histological variant of glioblastoma (WHO grade IV) with a predominance of bizarre, multinucleated giant cells, an occasionally abundant stromal reticulin network, and a high frequency of TP53 mutations. (WHO)

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for giant cell glioblastoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE1. Research is primarily sponsored by academic and government institutions.

109 publications have been identified in PubMed for giant cell glioblastoma. Research spans Review / Meta-Analysis (47%), Basic Science / Preclinical (29%), and Gene Therapy / Novel Therapeutics (11%).

Research Type	Count	% of Total
Research summaries	48

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:47 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:251579

GARD

Genetic and Rare Diseases Info Center

GARD:20705

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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giant cell glioblastoma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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