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giant cell reparative granuloma (GCLSB) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

giant cell reparative granuloma

MONDO:0006770

Also known as:GCLSBcentral giant cell (reparative) granulomacentral giant cell granuloma

Overview

A rare tumor-like lesion of the hands and feet characterized by the presence of hemorrhagic fibrous tissue, hemosiderin deposition, osteoclast-like giant cells which are irregularly distributed, and reactive bone formation. Pain and swelling are the most frequent symptoms. It may recur following curettage, but is usually cured after a second procedure.

Diagnosis

Biomarker and diagnostic research for giant cell reparative granuloma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for giant cell reparative granuloma.

76 publications have been identified in PubMed for giant cell reparative granuloma. Research spans Case Report / Case Series (47%), Review / Meta-Analysis (20%), and Epidemiology / Natural History (12%).

Research Type	Count	% of Total
Patient case studies	36	47%

Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 8:04 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

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giant cell reparative granuloma

Overview

Diagnosis

Research Landscape

Medical References

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Questions for Your Care Team

Questions for Your Care Team

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