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An aggressive type of endocrine tumor of the appendix presenting equally in males and females in the fifth decade of life and manifesting with a palpable mass and abdominal pain or acute appendicitis. Metastasis to the ovaries, peritoneum or right colon has usually already occurred in half of patients at the time of diagnosis.
Biomarker and diagnostic research for goblet cell carcinoma has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for goblet cell carcinoma.
75 publications have been identified in PubMed for goblet cell carcinoma. Research spans Case Report / Case Series (51%), Epidemiology / Natural History (20%), and Review / Meta-Analysis (12%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 38 | 51% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 11:53 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
15 |
20% |
Research summaries | 9 | 12% |
Laboratory research | 6 | 8% |
Testing and diagnosis research | 4 | 5% |
Clinical study results | 2 | 3% |
Other research | 1 | 1% |
Esparham A (2026). [PMID: 41796849](https://pubmed.ncbi.nlm.nih.gov/41796849/). *Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract*. [Case Report / Case Series]
Omote R (2026). [PMID: 42185729](https://pubmed.ncbi.nlm.nih.gov/42185729/). *Clin J Gastroenterol*. [Case Report / Case Series]
Krishnan SK (2026). [PMID: 42147504](https://pubmed.ncbi.nlm.nih.gov/42147504/). *Cureus*. [Epidemiology / Natural History]
Lin V (2026). [PMID: 41727240](https://pubmed.ncbi.nlm.nih.gov/41727240/). *Journal of surgical case reports*. [Review / Meta-Analysis]
Pattalachinti VK (2026). [PMID: 42081241](https://pubmed.ncbi.nlm.nih.gov/42081241/). *JAMA Netw Open*. [Epidemiology / Natural History]
Menon G (2026). [PMID: 28846286](https://pubmed.ncbi.nlm.nih.gov/28846286/). *Unknown Journal*. [Review / Meta-Analysis]
Iugai S (2026). [PMID: 41740516](https://pubmed.ncbi.nlm.nih.gov/41740516/). *European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology*. [Epidemiology / Natural History]
Nordström P (2026). [PMID: 41978805](https://pubmed.ncbi.nlm.nih.gov/41978805/). *J Surg Case Rep*. [Case Report / Case Series]
Hashimoto H (2026). [PMID: 41872678](https://pubmed.ncbi.nlm.nih.gov/41872678/). *Pathol Int*. [Case Report / Case Series]
Behzatoğlu K (2026). [PMID: 41557567](https://pubmed.ncbi.nlm.nih.gov/41557567/). *Pathobiology : journal of immunopathology, molecular and cellular biology*. [Basic Science / Preclinical]
AI-curated news mentioning goblet cell carcinoma
Updated Apr 9, 2026
A case report highlights the discovery of goblet cell adenocarcinoma in a patient with recurrent uncomplicated appendicitis. This finding underscores the importance of thorough investigation in similar cases to rule out underlying malignancies.