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Good syndrome, also known as thymoma-immunodeficiency, is a very rare acquired immunodeficiency syndrome characterized by the association of thymoma and combined B-cell and T-cell immunodeficiency of adult onset with increased susceptibility to infections.
Biomarker and diagnostic research for Good syndrome has been reported in the published literature.
Estimated prevalence: 1-9 in 100,000 (Uncommon).
No clinical trials have been registered for Good syndrome.
182 publications have been identified in PubMed for Good syndrome. Research spans Review / Meta-Analysis (51%), Case Report / Case Series (23%), and Basic Science / Preclinical (15%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 92 | 51% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:00 PM UTC
Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Good syndrome
42 |
23% |
Laboratory research | 27 | 15% |
Disease patterns and progression | 8 | 4% |
Testing and diagnosis research | 6 | 3% |
Other research | 4 | 2% |
Clinical study results | 2 | 1% |
New treatment approaches | 1 | 1% |
Nakashima S (2026). [PMID: 41671609](https://pubmed.ncbi.nlm.nih.gov/41671609/). *Journal of neuroimmunology*. [Case Report / Case Series]
Sun S (2026). [PMID: 41622196](https://pubmed.ncbi.nlm.nih.gov/41622196/). *Journal of cardiothoracic surgery*. [Case Report / Case Series]
Gąsiorowska J (2026). [PMID: 42023627](https://pubmed.ncbi.nlm.nih.gov/42023627/). *Pediatr Endocrinol Diabetes Metab*. [Review / Meta-Analysis]
Papazachariou A (2026). [PMID: 41128447](https://pubmed.ncbi.nlm.nih.gov/41128447/). *Curr Opin Clin Nutr Metab Care*. [Review / Meta-Analysis]
Chen Y (2026). [PMID: 42112326](https://pubmed.ncbi.nlm.nih.gov/42112326/). *Front Immunol*. [Basic Science / Preclinical]
Canaslan K (2026). [PMID: 41843177](https://pubmed.ncbi.nlm.nih.gov/41843177/). *Cancer Immunol Immunother*. [Review / Meta-Analysis]
Salimi P (2026). [PMID: 41663136](https://pubmed.ncbi.nlm.nih.gov/41663136/). *CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne*. [Case Report / Case Series]
Jarrold D (2026). [PMID: 41979311](https://pubmed.ncbi.nlm.nih.gov/41979311/). *Ann Card Anaesth*. [Case Report / Case Series]
Rajesh AE (2026). [PMID: 41666356](https://pubmed.ncbi.nlm.nih.gov/41666356/). *Retinal cases & brief reports*. [Case Report / Case Series]
Ghazizadeh M (2026). [PMID: 41938022](https://pubmed.ncbi.nlm.nih.gov/41938022/). *Case Rep Hematol*. [Case Report / Case Series]
AI-curated news mentioning Good syndrome
Updated Jul 17, 2026
A case report highlights the clinical manifestations of Good syndrome, specifically diarrhea and dyspnea. This report contributes to the understanding of this rare immunodeficiency disorder.