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A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes.
Biomarker and diagnostic research for hematopoietic and lymphoid cell neoplasm has been reported in the published literature.
135 clinical trials registered, 39 recruiting. Interventions under study include other interventions, drug therapy, procedural interventions, and biologic therapy. Pipeline includes 3 PHASE4, 5 PHASE3, 32 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT02586389](https://clinicaltrials.gov/study/NCT02586389) |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 1:11 PM UTC
Specimen Collection from Patients with Non-Hematologic Cancer for Use in Development of a Liquid Biopsy Assay |
— |
Sequenom, Inc. |
RECRUITING |
[NCT06125483](https://clinicaltrials.gov/study/NCT06125483) | TBI/Flu/Bu/Mel Combined With Secondary UCBT in Patients With Hematological Malignancies Who Relapsed After Allo-HSCT | NA | The First Affiliated Hospital of Soochow University | RECRUITING |
[NCT05334069](https://clinicaltrials.gov/study/NCT05334069) | Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection | — | Alliance for Clinical Trials in Oncology | RECRUITING |
[NCT04678427](https://clinicaltrials.gov/study/NCT04678427) | Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant | NA | M.D. Anderson Cancer Center | RECRUITING |
[NCT06587100](https://clinicaltrials.gov/study/NCT06587100) | Wearable Activity Tracking to Curb Hospitalizations | — | University of California, San Francisco | RECRUITING |
313 publications have been identified in PubMed for hematopoietic and lymphoid cell neoplasm. Research spans Review / Meta-Analysis (48%), Epidemiology / Natural History (15%), and Basic Science / Preclinical (9%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 150 | 48% |
Disease patterns and progression | 46 | 15% |
Laboratory research | 27 | 9% |
New treatment approaches | 26 | 8% |
Testing and diagnosis research | 22 | 7% |
Clinical study results | 16 | 5% |
Other research | 15 | 5% |
Patient case studies | 11 | 4% |
Patel K (2026). [PMID: 42225588](https://pubmed.ncbi.nlm.nih.gov/42225588/). *Cancer*. [Review / Meta-Analysis]
Lemgart VT (2026). [PMID: 41691371](https://pubmed.ncbi.nlm.nih.gov/41691371/). *Mol Ther*. [Basic Science / Preclinical]
Tran VL (2026). [PMID: 41831669](https://pubmed.ncbi.nlm.nih.gov/41831669/). *Exp Hematol*. [Review / Meta-Analysis]
Wisal AMM (2026). [PMID: 41389949](https://pubmed.ncbi.nlm.nih.gov/41389949/). *Biochim Biophys Acta Rev Cancer*. [Review / Meta-Analysis]
Hu H (2026). [PMID: 42033215](https://pubmed.ncbi.nlm.nih.gov/42033215/). *Cancer Biol Ther*. [Review / Meta-Analysis]
Frisardi V (2026). [PMID: 40956507](https://pubmed.ncbi.nlm.nih.gov/40956507/). *Eur Geriatr Med*. [Review / Meta-Analysis]
Pan Y (2026). [PMID: 41956548](https://pubmed.ncbi.nlm.nih.gov/41956548/). *Hum Vaccin Immunother*. [Review / Meta-Analysis]
Chanias I (2026). [PMID: 41650719](https://pubmed.ncbi.nlm.nih.gov/41650719/). *Leuk Res*. [Review / Meta-Analysis]
Smith TH (2026). [PMID: 41242614](https://pubmed.ncbi.nlm.nih.gov/41242614/). *Mod Pathol*. [Diagnostic / Biomarker]
Muth A (2026). [PMID: 41763222](https://pubmed.ncbi.nlm.nih.gov/41763222/). *Med*. [Review / Meta-Analysis]