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hepatosplenic T-cell lymphoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

hepatosplenic T-cell lymphoma

MONDO:0019474

Also known as:Hepatosplenic gamma/Delta T-cell lymphomaHSTCL

Find Clinical TrialsTrials

Overview

An extranodal, mature T-cell non-Hodgkin lymphoma that originates from cytotoxic T-cells, usually of gamma/delta T-cell type. It is characterized by the presence of medium-size neoplastic lymphocytes infiltrating the hepatic sinusoids. A similar infiltrating pattern is also present in the spleen and bone marrow that are usually involved at the time of the diagnosis.

Clinical Trials8 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for hepatosplenic T-cell lymphoma has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

8 clinical trials registered, 3 recruiting. Interventions under study include drug therapy, other interventions, and biologic therapy. Pipeline includes 2 PHASE2, 4 PHASE1, 1 NA. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT03598998](https://clinicaltrials.gov/study/NCT03598998)

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:00 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:86882

GARD

Genetic and Rare Diseases Info Center

GARD:19077

Questions for Your Care Team

→Are any of the 8 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Patient case studies	16	53%
Research summaries	7	23%
Disease patterns and progression	3	10%
Testing and diagnosis research	2	7%
Clinical study results	2	7%

hepatosplenic T-cell lymphoma

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications