Hereditary angioedema type 2 (HAE 2) is a form of hereditary angioedema characterized by acute edema in subcutaneous tissues, viscera and/or the upper airway.
Comprehensive, easy-to-understand information about this condition
How we create this content →The limited documentation surrounding hereditary angioedema type 2 is largely due to its rarity. Conditions like HAE 2 affect a small number of individuals, making it difficult to conduct large-scale clinical studies. Additionally, the lack of identified genetic markers and a clear inheritance pattern complicates the understanding of its clinical presentation and management strategies.
To navigate hereditary angioedema type 2, consider consulting with an allergist or immunologist who specializes in angioedema and related disorders. They can provide tailored management strategies and access to the latest research. Additionally, you may explore participation in clinical trials, which can be found on ClinicalTrials.gov. Although no specific patient organizations are identified for HAE 2, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information.
There are currently four active clinical trials focused on hereditary angioedema type 2, which may offer new insights and potential treatment options. Notably, there is one FDA-approved treatment, donidalorsen, and several orphan drugs in development, including a gene therapy using an adeno-associated virus vector targeting the C1-esterase inhibitor gene and small interfering RNA targeting prekallikrein. For more information on ongoing trials, visit ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=hereditary%20angioedema%20type%202.
Actionable guidance for navigating care for hereditary angioedema type 2
To navigate hereditary angioedema type 2, consider consulting with an allergist or immunologist who specializes in angioedema and related disorders. They can provide tailored management strategies and access to the latest research. Additionally, you may explore participation in clinical trials, which can be found on ClinicalTrials.gov. Although no specific patient organizations are identified for HAE 2, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding hereditary angioedema type 2 is largely due to its rarity. Conditions like HAE 2 affect a small number of individuals, making it difficult to conduct large-scale clinical studies. Additionally, the lack of identified genetic markers and a clear inheritance pattern complicates the understanding of its clinical presentation and management strategies.
To navigate hereditary angioedema type 2, consider consulting with an allergist or immunologist who specializes in angioedema and related disorders. They can provide tailored management strategies and access to the latest research. Additionally, you may explore participation in clinical trials, which can be found on ClinicalTrials.gov. Although no specific patient organizations are identified for HAE 2, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information.
There are currently four active clinical trials focused on hereditary angioedema type 2, which may offer new insights and potential treatment options. Notably, there is one FDA-approved treatment, donidalorsen, and several orphan drugs in development, including a gene therapy using an adeno-associated virus vector targeting the C1-esterase inhibitor gene and small interfering RNA targeting prekallikrein. For more information on ongoing trials, visit ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=hereditary%20angioedema%20type%202.
Actionable guidance for navigating care for hereditary angioedema type 2
To navigate hereditary angioedema type 2, consider consulting with an allergist or immunologist who specializes in angioedema and related disorders. They can provide tailored management strategies and access to the latest research. Additionally, you may explore participation in clinical trials, which can be found on ClinicalTrials.gov. Although no specific patient organizations are identified for HAE 2, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
The limited documentation surrounding hereditary angioedema type 2 is largely due to its rarity. Conditions like HAE 2 affect a small number of individuals, making it difficult to conduct large-scale clinical studies. Additionally, the lack of identified genetic markers and a clear inheritance pattern complicates the understanding of its clinical presentation and management strategies.
To navigate hereditary angioedema type 2, consider consulting with an allergist or immunologist who specializes in angioedema and related disorders. They can provide tailored management strategies and access to the latest research. Additionally, you may explore participation in clinical trials, which can be found on ClinicalTrials.gov. Although no specific patient organizations are identified for HAE 2, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information.
There are currently four active clinical trials focused on hereditary angioedema type 2, which may offer new insights and potential treatment options. Notably, there is one FDA-approved treatment, donidalorsen, and several orphan drugs in development, including a gene therapy using an adeno-associated virus vector targeting the C1-esterase inhibitor gene and small interfering RNA targeting prekallikrein. For more information on ongoing trials, visit ClinicalTrials.gov: https://clinicaltrials.gov/search?cond=hereditary%20angioedema%20type%202.
Actionable guidance for navigating care for hereditary angioedema type 2
To navigate hereditary angioedema type 2, consider consulting with an allergist or immunologist who specializes in angioedema and related disorders. They can provide tailored management strategies and access to the latest research. Additionally, you may explore participation in clinical trials, which can be found on ClinicalTrials.gov. Although no specific patient organizations are identified for HAE 2, resources like the National Organization for Rare Disorders (NORD) at rarediseases.org can offer support and information.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 31, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
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