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hereditary continuous muscle fiber activity - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

hereditary continuous muscle fiber activity

MONDO:0019943

Also known as:continuous muscle fiber activity hereditarycontinuous muscle fiber activity, hereditarycontinuous muscle fibre activity hereditary

Overview

Hereditary continuous muscle fiber activity is a rare, non-dystrophic myopathy characterized by generalized myokymia and increased muscle tone associated with delayed motor milestones, leg stiffness, spastic gait, hyperreflexia and Babinski sign. Symptoms may be worsened by febrile illness or anesthesia.

ResearchLimited published research (7 articles)

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for hereditary continuous muscle fiber activity.

7 publications have been identified in PubMed for hereditary continuous muscle fiber activity. Research spans Other (29%), Basic Science / Preclinical (29%), and Epidemiology / Natural History (29%).

Recent Publications

Katirji B (2026). [PMID: 42124386](https://pubmed.ncbi.nlm.nih.gov/42124386/). *Muscle Nerve*. [Basic Science / Preclinical]
Spiliopoulos KC (2025). [PMID: 40009145](https://pubmed.ncbi.nlm.nih.gov/40009145/). *Neurol Sci*. [Case Report / Case Series]
Chaillet KS (2025). [PMID: 39433288](https://pubmed.ncbi.nlm.nih.gov/39433288/). *Psychol Health Med*. [Epidemiology / Natural History]
Ravara B (2025). [PMID: 40047227](https://pubmed.ncbi.nlm.nih.gov/40047227/). *Eur J Transl Myol*. [Other]
Riuzzi F (2024). [PMID: 38651523](https://pubmed.ncbi.nlm.nih.gov/38651523/). *Eur J Transl Myol*. [Other]

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:30 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:972

GARD

Genetic and Rare Diseases Info Center

GARD:1512

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
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hereditary continuous muscle fiber activity

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team