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hereditary diffuse gastric adenocarcinoma (FDGC) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

hereditary diffuse gastric adenocarcinoma

MONDO:0007648

Also known as:FDGCHDGCfamilial diffuse cancer of stomach

Find Clinical TrialsTrials

Overview

An autosomal dominant inherited adenocarcinoma that arises from the gastric mucosa and is characterized by the presence of poorly cohesive malignant cells and absence of glandular formations.

Clinical Trials1 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for hereditary diffuse gastric adenocarcinoma has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

258 publications have been identified in PubMed for hereditary diffuse gastric adenocarcinoma. Kisho has analyzed 156 by research type. Research spans Review / Meta-Analysis (36%), Basic Science / Preclinical (17%), and Diagnostic / Biomarker (15%).

Research Type	Count	% of Total
Research summaries	56

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 3:03 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:26106

GARD

Genetic and Rare Diseases Info Center

GARD:10900

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Kisho

hereditary diffuse gastric adenocarcinoma

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Hereditary Diffuse Gastric Cancer With Poorly Differentiated Gallbladder Adenocarcinoma: A Case Report Suggesting Carcinogenesis in the Stomach and Gallbladder Caused by a Pathogenic Germline Variant in CDH1.

hereditary diffuse gastric adenocarcinoma

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Hereditary Diffuse Gastric Cancer With Poorly Differentiated Gallbladder Adenocarcinoma: A Case Report Suggesting Carcinogenesis in the Stomach and Gallbladder Caused by a Pathogenic Germline Variant in CDH1.