SCN11A function has not been fully characterized.

Hereditary sensory and autonomic neuropathy type 7 is associated with mutations in the SCN11A gene on chromosome 3.

Genetic testing for SCN11A is available. Testing is considered confirmatory for diagnosis.

Phenotype severity distribution: 4 always present features.

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

No clinical trials have been registered for hereditary sensory and autonomic neuropathy type 7.

11 publications have been identified in PubMed for hereditary sensory and autonomic neuropathy type 7. Research spans Case Report / Case Series (55%), Basic Science / Preclinical (18%), and Review / Meta-Analysis (9%).

Recent Publications

• Bar-Aluma BE (2025). [PMID: 40555858](https://pubmed.ncbi.nlm.nih.gov/40555858/). *Calcif Tissue Int*. [Epidemiology / Natural History]

• Kjellberg A (2025). [PMID: 39789590](https://pubmed.ncbi.nlm.nih.gov/39789590/). *J Med Case Rep*. [Case Report / Case Series]

• Ahmad R (2025). [PMID: 40938507](https://pubmed.ncbi.nlm.nih.gov/40938507/). *Neurol Sci*. [Case Report / Case Series]

• Fu X (2025). [PMID: 40849231](https://pubmed.ncbi.nlm.nih.gov/40849231/). *J Neuromuscul Dis*. [Basic Science / Preclinical]

• Zhu Y (2025). [PMID: 40296002](https://pubmed.ncbi.nlm.nih.gov/40296002/). *Orphanet J Rare Dis*. [Case Report / Case Series]

• Cashman CR (2025). [PMID: 40400204](https://pubmed.ncbi.nlm.nih.gov/40400204/). *Ann Clin Transl Neurol*. [Basic Science / Preclinical]

• Higashimoto T (2024). [PMID: 39465509](https://pubmed.ncbi.nlm.nih.gov/39465509/). *Mol Genet Genomic Med*. [Case Report / Case Series]

• Naghinejad M (2024). [PMID: 39441469](https://pubmed.ncbi.nlm.nih.gov/39441469/). *J Mol Neurosci*. [Case Report / Case Series]

• Sarveswaran N (2024). [PMID: 38591490](https://pubmed.ncbi.nlm.nih.gov/38591490/). *Br J Dermatol*. [Case Report / Case Series]

• Drăghici M (2024). [PMID: 39768907](https://pubmed.ncbi.nlm.nih.gov/39768907/). *Medicina (Kaunas)*. [Clinical Trial Publication]