Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

hereditary thrombophilia due to congenital protein S deficiency - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

hereditary thrombophilia due to congenital protein S deficiency

MONDO:0019144

Also known as:autosomal recessive thrombophilia due to congenital protein S deficiencysevere hereditary thrombophilia due to congenital protein S deficiency

Overview

Congenital protein S deficiency is an inherited coagulation disorder characterized by recurrent venous thrombosis symptoms due to reduced synthesis and/or activity levels of protein S.

ResearchLimited published research (4 articles)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for hereditary thrombophilia due to congenital protein S deficiency.

4 publications have been identified in PubMed for hereditary thrombophilia due to congenital protein S deficiency. Research spans Case Report / Case Series (75%) and Epidemiology / Natural History (25%).

Recent Publications

Rodriguez Espada A (2026). [PMID: 41026970](https://pubmed.ncbi.nlm.nih.gov/41026970/). *Blood advances*. [Epidemiology / Natural History]
Ogawa S (2025). [PMID: 41542355](https://pubmed.ncbi.nlm.nih.gov/41542355/). *NMC case report journal*. [Case Report / Case Series]
Nanda Palanisamy N (2025). [PMID: 40084314](https://pubmed.ncbi.nlm.nih.gov/40084314/). *Cureus*. [Case Report / Case Series]
Marco-Rico A (2024). [PMID: 39070969](https://pubmed.ncbi.nlm.nih.gov/39070969/). *Journal of blood medicine*. [Case Report / Case Series]

Data assembled from 3 of 12 sources · Last updated Sep 21, 2026, 12:36 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:743

GARD

Genetic and Rare Diseases Info Center

GARD:16543

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

hereditary thrombophilia due to congenital protein S deficiency

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team