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Biomarker and diagnostic research for high bone mass osteogenesis imperfecta has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for high bone mass osteogenesis imperfecta.
39 publications have been identified in PubMed for high bone mass osteogenesis imperfecta. Research spans Basic Science / Preclinical (26%), Clinical Trial Publication (23%), and Review / Meta-Analysis (18%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 10 | 26% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 8:55 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Clinical study results
9 |
23% |
Research summaries | 7 | 18% |
Disease patterns and progression | 6 | 15% |
Patient case studies | 3 | 8% |
Testing and diagnosis research | 2 | 5% |
New treatment approaches | 2 | 5% |
Bayraktar HEN (2026). [PMID: 41491132](https://pubmed.ncbi.nlm.nih.gov/41491132/). *European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society*. [Epidemiology / Natural History]
Padidela R (2026). [PMID: 42162256](https://pubmed.ncbi.nlm.nih.gov/42162256/). *Nat Rev Endocrinol*. [Review / Meta-Analysis]
Brigato P (2026). [PMID: 41854906](https://pubmed.ncbi.nlm.nih.gov/41854906/). *European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society*. [Review / Meta-Analysis]
Miller CA (2025). [PMID: 39989289](https://pubmed.ncbi.nlm.nih.gov/39989289/). *Anatomical record (Hoboken, N.J. : 2007)*. [Gene Therapy / Novel Therapeutics]
Debaenst S (2025). [PMID: 39817421](https://pubmed.ncbi.nlm.nih.gov/39817421/). *eLife*. [Basic Science / Preclinical]
Mulcrone JE (2025). [PMID: 41378917](https://pubmed.ncbi.nlm.nih.gov/41378917/). *Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research*. [Gene Therapy / Novel Therapeutics]
Liu J (2025). [PMID: 39994027](https://pubmed.ncbi.nlm.nih.gov/39994027/). *Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA*. [Review / Meta-Analysis]
Xie CL (2025). [PMID: 40192033](https://pubmed.ncbi.nlm.nih.gov/40192033/). *Advanced science (Weinheim, Baden-Wurttemberg, Germany)*. [Basic Science / Preclinical]
Blandin C (2025). [PMID: 39514768](https://pubmed.ncbi.nlm.nih.gov/39514768/). *The Journal of clinical endocrinology and metabolism*. [Clinical Trial Publication]
Jain C (2025). [PMID: 41079170](https://pubmed.ncbi.nlm.nih.gov/41079170/). *Journal of the Pediatric Orthopaedic Society of North America*. [Basic Science / Preclinical]