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High-grade neuroendocrine carcinoma of the cervix uteri is a rare, aggressive, primary cervical neoplasm, originating from neuroendocrine cells present in the lining epithelium of the cervix, characterized, macroscopically, by usually large lesions, sometimes with a barrel-shaped appearance. Patients often present with abnormal vaginal bleeding or discharge, pelvic/abdominal pain, post-coital spotting and/or dysuria, while symptoms related to carcinoid syndrome are not frequent.
Biomarker and diagnostic research for high-grade neuroendocrine carcinoma of the cervix uteri has been reported in the published literature.
No clinical trials have been registered for high-grade neuroendocrine carcinoma of the cervix uteri.
75 publications have been identified in PubMed for high-grade neuroendocrine carcinoma of the cervix uteri. Research spans Case Report / Case Series (39%), Review / Meta-Analysis (19%), and Epidemiology / Natural History (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 29 | 39% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:39 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries |
14 |
19% |
Disease patterns and progression | 10 | 14% |
Testing and diagnosis research | 8 | 11% |
Laboratory research | 5 | 7% |
New treatment approaches | 4 | 5% |
Clinical study results | 3 | 4% |
Other research | 1 | 1% |
Wakana K (2026). [PMID: 42152606](https://pubmed.ncbi.nlm.nih.gov/42152606/). *J Obstet Gynaecol Res*. [Case Report / Case Series]
Kobayashi M (2026). [PMID: 41483492](https://pubmed.ncbi.nlm.nih.gov/41483492/). *Int J Gynecol Cancer*. [Epidemiology / Natural History]
Satala CB (2026). [PMID: 42196939](https://pubmed.ncbi.nlm.nih.gov/42196939/). *Diagnostics (Basel)*. [Review / Meta-Analysis]
Jia M (2026). [PMID: 41792048](https://pubmed.ncbi.nlm.nih.gov/41792048/). *Cancer Med*. [Diagnostic / Biomarker]
Ren Y (2026). [PMID: 41474616](https://pubmed.ncbi.nlm.nih.gov/41474616/). *Cancer Med*. [Epidemiology / Natural History]
Yoh K (2026). [PMID: 42111278](https://pubmed.ncbi.nlm.nih.gov/42111278/). *Gynecol Oncol Rep*. [Case Report / Case Series]
Kobayashi M (2026). [PMID: 41932141](https://pubmed.ncbi.nlm.nih.gov/41932141/). *Int J Gynecol Cancer*. [Epidemiology / Natural History]
Elsafy H (2026). [PMID: 41428750](https://pubmed.ncbi.nlm.nih.gov/41428750/). *Int J Surg Pathol*. [Case Report / Case Series]
Kang Y (2026). [PMID: 42118669](https://pubmed.ncbi.nlm.nih.gov/42118669/). *Cancer Control*. [Epidemiology / Natural History]
Kasajima A (2026). [PMID: 41483302](https://pubmed.ncbi.nlm.nih.gov/41483302/). *Virchows Arch*. [Review / Meta-Analysis]