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Nephrotic syndrome for which no cause has been identified.
Biomarker and diagnostic research for idiopathic nephrotic syndrome has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
9 clinical trials registered, 4 recruiting. Interventions under study include other interventions and drug therapy. Pipeline includes 1 PHASE4, 2 PHASE3. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT06635720](https://clinicaltrials.gov/study/NCT06635720) |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:55 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
REduced-dose Steroid PrOtocol for Childhood Nephrotic SyndromE (RESPONSE)
PHASE3 |
The Hospital for Sick Children |
ACTIVE_NOT_RECRUITING |
[NCT07151456](https://clinicaltrials.gov/study/NCT07151456) | Short-term gluCOCOrticoid in Adult STEROID-sensitive Nephrotic Syndrome: The COCO-ASTEROID Study | PHASE4 | First Affiliated Hospital of Wenzhou Medical University | NOT_YET_RECRUITING |
[NCT06334692](https://clinicaltrials.gov/study/NCT06334692) | Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome | — | Mario Negri Institute for Pharmacological Research | RECRUITING |
[NCT06325137](https://clinicaltrials.gov/study/NCT06325137) | Transcriptome Analysis in Idiopathic Nephrotic Syndrome: Steroid Responsiveness | — | IRCCS Burlo Garofolo | UNKNOWN |
[NCT05505500](https://clinicaltrials.gov/study/NCT05505500) | Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome. | — | University of Michigan | RECRUITING |
162 publications have been identified in PubMed for idiopathic nephrotic syndrome. Research spans Clinical Trial Publication (24%), Basic Science / Preclinical (22%), and Epidemiology / Natural History (15%).
Research Type | Count | % of Total |
|---|---|---|
Clinical study results | 38 | 24% |
Laboratory research | 35 | 22% |
Disease patterns and progression | 24 | 15% |
Testing and diagnosis research | 22 | 14% |
Research summaries | 16 | 10% |
Patient case studies | 12 | 8% |
Other research | 5 | 3% |
New treatment approaches | 4 | 3% |
Hammad AM (2026). [PMID: 41914989](https://pubmed.ncbi.nlm.nih.gov/41914989/). *Saudi J Kidney Dis Transpl*. [Diagnostic / Biomarker]
Luo Y (2026). [PMID: 41772268](https://pubmed.ncbi.nlm.nih.gov/41772268/). *Journal of clinical immunology*. [Epidemiology / Natural History]
van den Berge BT (2026). [PMID: 41510006](https://pubmed.ncbi.nlm.nih.gov/41510006/). *Kidney Med*. [Basic Science / Preclinical]
Sandokji I (2026). [PMID: 41971034](https://pubmed.ncbi.nlm.nih.gov/41971034/). *Int J Gen Med*. [Epidemiology / Natural History]
Hengel FE (2026). [PMID: 41736774](https://pubmed.ncbi.nlm.nih.gov/41736774/). *Kidney Int Rep*. [Clinical Trial Publication]
Lu L (2026). [PMID: 41506446](https://pubmed.ncbi.nlm.nih.gov/41506446/). *Transl Res*. [Basic Science / Preclinical]
Ulu E (2026). [PMID: 41258111](https://pubmed.ncbi.nlm.nih.gov/41258111/). *Pediatr Nephrol*. [Diagnostic / Biomarker]
Kamigaki Y (2026). [PMID: 41735917](https://pubmed.ncbi.nlm.nih.gov/41735917/). *BMC Nephrol*. [Basic Science / Preclinical]
Saha A (2026). [PMID: 40768034](https://pubmed.ncbi.nlm.nih.gov/40768034/). *Indian Pediatr*. [Clinical Trial Publication]
Gurevich E (2026). [PMID: 42141295](https://pubmed.ncbi.nlm.nih.gov/42141295/). *Pediatr Nephrol*. [Basic Science / Preclinical]