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Inflammatory myopathy with abundant macrophages is a rare inflammatory myopathy characterized by diffuse destructive infiltration of CD68+ macrophages into the fascia rather than muscle fibers in muscle biopsies, proximal muscle weakness and myalgia with or without scaly dermatomyositis-like or atypical non-dermatomyositis-like skin lesions, elevation of creatine kinase levels and thickening of muscle fascia in muscle MRI.
No clinical trials have been registered for inflammatory myopathy with abundant macrophages.
4 publications have been identified in PubMed for inflammatory myopathy with abundant macrophages. Research spans Basic Science / Preclinical (75%) and Review / Meta-Analysis (25%).
Kleefeld F (2026). [PMID: 41934478](https://pubmed.ncbi.nlm.nih.gov/41934478/). *Acta Neuropathol*. [Basic Science / Preclinical]
Pereira Bacares ME (2025). [PMID: 39839721](https://pubmed.ncbi.nlm.nih.gov/39839721/). *Journal of toxicologic pathology*. [Basic Science / Preclinical]
Bamaga A (2025). [PMID: 39973451](https://pubmed.ncbi.nlm.nih.gov/39973451/). *Journal of neuromuscular diseases*. [Review / Meta-Analysis]
Zhang H (2025). [PMID: 40035761](https://pubmed.ncbi.nlm.nih.gov/40035761/). *Proceedings of the National Academy of Sciences of the United States of America*. [Basic Science / Preclinical]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:42 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
AI-curated news mentioning inflammatory myopathy with abundant macrophages
Updated Jan 28, 2026
The MIHRA initiative focuses on gathering patient-rooted insights to shape research in myositis and related conditions. Sponsored by multiple organizations, including Myositis International and The Myositis Association, this project emphasizes qualitative investigations to better understand patient experiences.