Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

intellectual disability, autosomal recessive 25 (MRT25) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

intellectual disability, autosomal recessive 25

MONDO:0013708

Also known as:MRT25mental retardation, autosomal recessive 25

Overview

GeneticsAutosomal recessive

ResearchLimited published research (5 articles)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include: Moderate intellectual disability, Delayed speech and language development, Anxiety, and Motor delay.

Organ System	Phenotype Count	Example Features
Brain and nerves	3	Moderate intellectual disability, Delayed speech and language development, Anxiety

Explore clinical features

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for intellectual disability, autosomal recessive 25.

58 publications have been identified in PubMed for intellectual disability, autosomal recessive 25. Kisho has analyzed 5 by research type. Research spans Case Report / Case Series (60%) and Basic Science / Preclinical (40%).

Recent Publications

İpek R (2025). [PMID: 40014158](https://pubmed.ncbi.nlm.nih.gov/40014158/). *Neurogenetics*. [Case Report / Case Series]
Archer J (2025). [PMID: 40870020](https://pubmed.ncbi.nlm.nih.gov/40870020/). *Genes (Basel)*. [Case Report / Case Series]
Guillouet C (2025). [PMID: 40081376](https://pubmed.ncbi.nlm.nih.gov/40081376/). *Am J Hum Genet*. [Basic Science / Preclinical]
Dolu MH (2024). [PMID: 39051604](https://pubmed.ncbi.nlm.nih.gov/39051604/). *J Child Neurol*. [Case Report / Case Series]
Al Mutairi F (2024). [PMID: 39166056](https://pubmed.ncbi.nlm.nih.gov/39166056/). *Heliyon*. [Basic Science / Preclinical]

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:10 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:614346

GARD

Genetic and Rare Diseases Info Center

GARD:22561

Questions for Your Care Team

→Should my partner and I meet with a genetic counselor to discuss carrier status and family planning?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

intellectual disability, autosomal recessive 25

Overview

Clinical Presentation

Explore clinical features

Research Landscape

Recent Publications

Medical References

External Resources

OMIM

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team