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A congenital hypogonadotropic hypogonadism that is not part of a larger syndrome.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for isolated congenital hypogonadotropic hypogonadism.
7 publications have been identified in PubMed for isolated congenital hypogonadotropic hypogonadism. Research spans Review / Meta-Analysis (57%), Case Report / Case Series (29%), and Basic Science / Preclinical (14%).
Yıldız M (2025). [PMID: 39713897](https://pubmed.ncbi.nlm.nih.gov/39713897/). *Journal of clinical research in pediatric endocrinology*. [Review / Meta-Analysis]
Shah S (2025). [PMID: 41064665](https://pubmed.ncbi.nlm.nih.gov/41064665/). *JCEM case reports*. [Case Report / Case Series]
Zhang Y (2025). [PMID: 40696433](https://pubmed.ncbi.nlm.nih.gov/40696433/). *Human genomics*. [Review / Meta-Analysis]
Geraldes Paulino S (2025). [PMID: 40013223](https://pubmed.ncbi.nlm.nih.gov/40013223/). *Cureus*. [Case Report / Case Series]
Zhang Z (2025). [PMID: 39792770](https://pubmed.ncbi.nlm.nih.gov/39792770/). *Medicine*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 8:02 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Federici S (2024). [PMID: 39391877](https://pubmed.ncbi.nlm.nih.gov/39391877/). *Frontiers in endocrinology*. [Review / Meta-Analysis]
Rey RA (2024). [PMID: 38112850](https://pubmed.ncbi.nlm.nih.gov/38112850/). *Reviews in endocrine & metabolic disorders*. [Basic Science / Preclinical]
AI-curated news mentioning isolated congenital hypogonadotropic hypogonadism
Updated Mar 20, 2026
A new study evaluates a co-designed website aimed at improving resources for congenital hypogonadotropic hypogonadism. This initiative highlights the importance of patient involvement in developing educational tools for rare diseases.