LADD syndrome

LADD syndrome is a rare congenital disorder where multiple body systems are affected. People with this condition often have abnormalities in the tear (lacrimal) system, ears, salivary glands, teeth, and digits (fingers and toes). The observed anomalies include underdevelopment or absence of tear ducts, ear malformations often linked with hearing loss, dental differences, and unusual formation of the fingers or toes. This condition is known by several names including Lacrimoauriculodental syndrome and Levy-Hollister syndrome. It is part of a group of conditions that appear at birth and affect multiple organs, leading to a range of symptoms that can vary in severity among individuals.

People with LADD syndrome may experience issues with tear production due to underdeveloped or missing tear ducts. They might also have ear abnormalities that can lead to hearing difficulties, underdeveloped salivary glands, dental problems, and unusual digital (finger and toe) formation.

Information about causes is currently limited for this condition.

Information about treatment options is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about current research and future directions is currently limited for this condition.