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Features include: Heterotaxy, Situs inversus totalis, Growth abnormality, and Asplenia.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Growth and development | 1 | Growth abnormality |
Biomarker and diagnostic research for laterality defects, autosomal dominant has been reported in the published literature.
No clinical trials have been registered for laterality defects, autosomal dominant.
81 publications have been identified in PubMed for laterality defects, autosomal dominant. Kisho has analyzed 57 by research type. Research spans Basic Science / Preclinical (30%), Case Report / Case Series (26%), and Review / Meta-Analysis (18%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 17 | 30% |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 11:11 AM UTC
Online Mendelian Inheritance in Man
Patient case studies |
15 |
26% |
Research summaries | 10 | 18% |
Testing and diagnosis research | 5 | 9% |
Disease patterns and progression | 4 | 7% |
New treatment approaches | 4 | 7% |
Clinical study results | 2 | 4% |
Coppola F (2026). [PMID: 40841163](https://pubmed.ncbi.nlm.nih.gov/40841163/). *AJNR Am J Neuroradiol*. [Diagnostic / Biomarker]
Matur AV (2026). [PMID: 41469204](https://pubmed.ncbi.nlm.nih.gov/41469204/). *AJNR Am J Neuroradiol*. [Gene Therapy / Novel Therapeutics]
Fu S (2026). [PMID: 41757605](https://pubmed.ncbi.nlm.nih.gov/41757605/). *Nanoscale*. [Review / Meta-Analysis]
Hines TJ (2026). [PMID: 41889878](https://pubmed.ncbi.nlm.nih.gov/41889878/). *bioRxiv*. [Basic Science / Preclinical]
Sampath Kumar D (2026). [PMID: 41782702](https://pubmed.ncbi.nlm.nih.gov/41782702/). *Clin Nephrol Case Stud*. [Case Report / Case Series]
Selim Gel M (2026). [PMID: 41934306](https://pubmed.ncbi.nlm.nih.gov/41934306/). *Pak J Pharm Sci*. [Diagnostic / Biomarker]
Johari M (2026). [PMID: 41678358](https://pubmed.ncbi.nlm.nih.gov/41678358/). *Brain*. [Basic Science / Preclinical]
Roa-Escobar J (2026). [PMID: 40847817](https://pubmed.ncbi.nlm.nih.gov/40847817/). *Amyotroph Lateral Scler Frontotemporal Degener*. [Case Report / Case Series]
Cajamarca S (2026). [PMID: 42081096](https://pubmed.ncbi.nlm.nih.gov/42081096/). *Neuroradiology*. [Diagnostic / Biomarker]
Bokade CM (2025). [PMID: 41114066](https://pubmed.ncbi.nlm.nih.gov/41114066/). *J Cardiovasc Echogr*. [Case Report / Case Series]
AI-curated news mentioning laterality defects, autosomal dominant
Updated Mar 4, 2026
A new study identifies MGRN1 as linked to recessive heart and laterality defects, marking the first genotype-phenotype report in humans. This discovery enhances understanding of the genetic basis for these conditions.