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leiomyosarcoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

leiomyosarcoma

MONDO:0005058

Also known as:Leiomyosarcomasleiomyosarcoma (excluding uterine leiomyosarcoma)leiomyosarcoma - not uterine

Find Clinical TrialsTrials

Overview

An uncommon, aggressive malignant smooth muscle neoplasm, usually occurring in post-menopausal women. It is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory and myxoid leimyosarcomas.

Clinical Trials59 registered · 34 recruiting

Patient Orgs1 organizations · Leiomyosarcoma Support & Direct Research Foundation

Diagnosis

Biomarker and diagnostic research for leiomyosarcoma has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

59 clinical trials registered, 34 recruiting. Interventions under study include drug therapy, procedural interventions, other interventions, and biologic therapy. Pipeline includes 3 PHASE3, 27 PHASE2, 13 PHASE1. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT06849986](https://clinicaltrials.gov/study/NCT06849986)

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:01 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Patient Support

Patient Advocacy Groups

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Leiomyosarcoma Support & Direct Research FoundationPrimary Focus

USWebsite ↗

Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.

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Medical References

External Resources

Orphanet

European rare disease database

Orphanet:64720

GARD

Genetic and Rare Diseases Info Center

GARD:6880

Questions for Your Care Team

→Are any of the 59 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→How can I connect with Leiomyosarcoma Support & Direct Research Foundation and other patient organizations for support?

← Back to All Diseases

Research Type	Count	% of Total
Patient case studies	96	38%
Research summaries	43	17%
Laboratory research	34	13%
Clinical study results	30	12%
Disease patterns and progression	24	9%
Testing and diagnosis research	20	8%
New treatment approaches	6	2%
Other research	3	1%

Kisho

leiomyosarcoma

Overview

Diagnosis

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Management of Soft Tissue and Visceral Leiomyosarcomas.

Metastatic Leiomyosarcoma Involving Bone and Kidney in an Adult Budgerigar (Melopsittacus undulatus).

MMR deficient dedifferentiated endometrial carcinoma with synchronous uterine leiomyosarcoma: a rare collision tumour-case report and literature review.

leiomyosarcoma

Overview

Diagnosis

Prognosis

Research Landscape

Patient Support

Patient Advocacy Groups

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Management of Soft Tissue and Visceral Leiomyosarcomas.

Metastatic Leiomyosarcoma Involving Bone and Kidney in an Adult Budgerigar (Melopsittacus undulatus).

MMR deficient dedifferentiated endometrial carcinoma with synchronous uterine leiomyosarcoma: a rare collision tumour-case report and literature review.