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Features include: Chronic lymphatic leukemia.
Biomarker and diagnostic research for leukemia, chronic lymphocytic, susceptibility to, 2 has been reported in the published literature.
34 clinical trials registered, 16 recruiting. Interventions under study include drug therapy, other interventions, biologic therapy, and medical devices. Pipeline includes 5 PHASE3, 7 PHASE2, 12 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05602363](https://clinicaltrials.gov/study/NCT05602363) |
Data assembled from 5 of 12 sources · Last updated Oct 3, 2026, 5:10 PM UTC
Online Mendelian Inheritance in Man
AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma |
PHASE1 |
Carna Biosciences, Inc. |
RECRUITING |
[NCT06697184](https://clinicaltrials.gov/study/NCT06697184) | A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers. | PHASE1 | BeOne Medicines | RECRUITING |
[NCT05006716](https://clinicaltrials.gov/study/NCT05006716) | A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies | PHASE1 | BeOne Medicines | RECRUITING |
[NCT05536349](https://clinicaltrials.gov/study/NCT05536349) | Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT) | PHASE2 | M.D. Anderson Cancer Center | RECRUITING |
[NCT05643742](https://clinicaltrials.gov/study/NCT05643742) | A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies | PHASE1 | CRISPR Therapeutics AG | RECRUITING |
171 publications have been identified in PubMed for leukemia, chronic lymphocytic, susceptibility to, 2. Research spans Review / Meta-Analysis (42%), Basic Science / Preclinical (29%), and Epidemiology / Natural History (13%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 71 | 42% |
Laboratory research | 49 | 29% |
Disease patterns and progression | 22 | 13% |
Testing and diagnosis research | 9 | 5% |
New treatment approaches | 6 | 4% |
Other research | 5 | 3% |
Patient case studies | 5 | 3% |
Clinical study results | 4 | 2% |
Dell'Aversana C (2026). [PMID: 41724980](https://pubmed.ncbi.nlm.nih.gov/41724980/). *J Hematol Oncol*. [Gene Therapy / Novel Therapeutics]
Dingli D (2026). [PMID: 41416420](https://pubmed.ncbi.nlm.nih.gov/41416420/). *Future Oncol*. [Epidemiology / Natural History]
Che WI (2026). [PMID: 42192899](https://pubmed.ncbi.nlm.nih.gov/42192899/). *Cancers (Basel)*. [Epidemiology / Natural History]
Chen S (2026). [PMID: 42001546](https://pubmed.ncbi.nlm.nih.gov/42001546/). *Eur J Med Chem*. [Gene Therapy / Novel Therapeutics]
Martino EA (2026). [PMID: 41793184](https://pubmed.ncbi.nlm.nih.gov/41793184/). *Clin Transl Med*. [Review / Meta-Analysis]
Bieliński K (2026). [PMID: 42123307](https://pubmed.ncbi.nlm.nih.gov/42123307/). *Int J Mol Sci*. [Review / Meta-Analysis]
Böttcher M (2026). [PMID: 41486278](https://pubmed.ncbi.nlm.nih.gov/41486278/). *Signal Transduct Target Ther*. [Epidemiology / Natural History]
Hussain MA (2026). [PMID: 42048498](https://pubmed.ncbi.nlm.nih.gov/42048498/). *Pol Merkur Lekarski*. [Basic Science / Preclinical]
Gammaldi V (2026). [PMID: 41752960](https://pubmed.ncbi.nlm.nih.gov/41752960/). *Life (Basel)*. [Diagnostic / Biomarker]
Yang S (2026). [PMID: 41775175](https://pubmed.ncbi.nlm.nih.gov/41775175/). *Drug Resist Updat*. [Review / Meta-Analysis]