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A rare genetic form of low-renin hypertension characterized by hypertension associated with decreased plasma levels of potassium and aldosterone.
Biomarker and diagnostic research for Liddle syndrome has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
2 clinical trials registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
35 publications have been identified in PubMed for Liddle syndrome. Research spans Case Report / Case Series (49%), Review / Meta-Analysis (29%), and Basic Science / Preclinical (17%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 17 | 49% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:30 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Liddle syndrome
Research summaries |
10 |
29% |
Laboratory research | 6 | 17% |
Other research | 1 | 3% |
Testing and diagnosis research | 1 | 3% |
Miyoshi S (2026). [PMID: 41559498](https://pubmed.ncbi.nlm.nih.gov/41559498/). *J Nat Med*. [Basic Science / Preclinical]
Nakano Y (2026). [PMID: 41297713](https://pubmed.ncbi.nlm.nih.gov/41297713/). *Int J Antimicrob Agents*. [Review / Meta-Analysis]
Hisaka S (2026). [PMID: 41850297](https://pubmed.ncbi.nlm.nih.gov/41850297/). *Planta Med*. [Diagnostic / Biomarker]
Nakayama T (2026). [PMID: 41983628](https://pubmed.ncbi.nlm.nih.gov/41983628/). *Pediatr Int*. [Case Report / Case Series]
Murphy L (2026). [PMID: 30725596](https://pubmed.ncbi.nlm.nih.gov/30725596/). *Unknown Journal*. [Review / Meta-Analysis]
Vecino-Pérez M (2026). [PMID: 42123522](https://pubmed.ncbi.nlm.nih.gov/42123522/). *Int J Mol Sci*. [Review / Meta-Analysis]
Ma T (2026). [PMID: 42147312](https://pubmed.ncbi.nlm.nih.gov/42147312/). *Front Pharmacol*. [Review / Meta-Analysis]
Frindt G (2026). [PMID: 41500518](https://pubmed.ncbi.nlm.nih.gov/41500518/). *American journal of physiology. Renal physiology*. [Review / Meta-Analysis]
Mulatero P (2026). [PMID: 41638800](https://pubmed.ncbi.nlm.nih.gov/41638800/). *Vitamins and hormones*. [Other]
Nakao S (2026). [PMID: 41534754](https://pubmed.ncbi.nlm.nih.gov/41534754/). *Journal of ethnopharmacology*. [Basic Science / Preclinical]