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Lissencephaly with cerebellar hypoplasia type B (LCHb) is a form of lissencephaly with cerebellar hypoplasia characterized by subtle microcephaly, hypotonia and neurological and cognitive development delay. Hippocampal malformation is a characteristic imaging feature of LCHb.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for lissencephaly with cerebellar hypoplasia type B.
4 publications have been identified in PubMed for lissencephaly with cerebellar hypoplasia type B. Research spans Case Report / Case Series (75%) and Review / Meta-Analysis (25%).
Lepri FR (2025). [PMID: 41249097](https://pubmed.ncbi.nlm.nih.gov/41249097/). *Prenat Diagn*. [Case Report / Case Series]
Newman JM (2025). [PMID: 40974083](https://pubmed.ncbi.nlm.nih.gov/40974083/). *J Neuropathol Exp Neurol*. [Case Report / Case Series]
Hayashi K (2024). [PMID: 39452687](https://pubmed.ncbi.nlm.nih.gov/39452687/). *Neurol Int*. [Case Report / Case Series]
Pogledic I (2024). [PMID: 39054600](https://pubmed.ncbi.nlm.nih.gov/39054600/). *Brain*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 1:33 PM UTC
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