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littoral cell angioma of the spleen (LCA) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

littoral cell angioma of the spleen

MONDO:0023650

Also known as:LCAlittoral cell angioma

Overview

Littoral cell angioma is a rare primary vascular neoplasm of the spleen, composed of littoral cells that line the splenic sinuses of the red pulp. It was thought to be a benign, incidental lesion. However, many recent reports have described it to be a malignant lesion with congenital and immunological associations. The definitive diagnosis can only be made after histology and immunohistochemistry studies.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for littoral cell angioma of the spleen.

16 publications have been identified in PubMed for littoral cell angioma of the spleen. Research spans Case Report / Case Series (75%), Review / Meta-Analysis (13%), and Other (6%).

Research Type	Count	% of Total
Patient case studies	12	75%
Research summaries	2

Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 11:35 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:9714

Questions for Your Care Team

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littoral cell angioma of the spleen

Overview

Research Landscape

Medical References

External Resources

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications