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Livedoid vasculopathy is a blood vessel disorder that causes painful ulcers and scarring (atrophie blanche) on the feet and lower legs. These symptoms can persist for months to years and the ulcers often recur.Livedoid vasculopathy lesions appear as painful red or purple marks and spots that may progress to small, tender, irregular ulcers. Symptoms tend to worsen in the winter and summer months, and affect women more often then men. Livedoid vasculopathy may occur alone or in combination with another condition, such as lupus or thrombophilia.
Biomarker and diagnostic research for livedoid vasculopathy has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for livedoid vasculopathy.
210 publications have been identified in PubMed for livedoid vasculopathy. Kisho has analyzed 99 by research type. Research spans Review / Meta-Analysis (33%), Case Report / Case Series (22%), and Epidemiology / Natural History (20%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 33 | 33% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 2:11 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Patient case studies
22 |
22% |
Disease patterns and progression | 20 | 20% |
Clinical study results | 8 | 8% |
Testing and diagnosis research | 7 | 7% |
Other research | 5 | 5% |
Laboratory research | 2 | 2% |
New treatment approaches | 2 | 2% |
Hysa E (2026). [PMID: 41117362](https://pubmed.ncbi.nlm.nih.gov/41117362/). *Eur J Clin Invest*. [Review / Meta-Analysis]
Liu Y (2026). [PMID: 41527208](https://pubmed.ncbi.nlm.nih.gov/41527208/). *J Cutan Med Surg*. [Clinical Trial Publication]
Ban F (2026). [PMID: 41482702](https://pubmed.ncbi.nlm.nih.gov/41482702/). *J Dtsch Dermatol Ges*. [Epidemiology / Natural History]
Bekoju B (2026). [PMID: 42058336](https://pubmed.ncbi.nlm.nih.gov/42058336/). *Cureus*. [Case Report / Case Series]
Criado GJ (2026). [PMID: 41875726](https://pubmed.ncbi.nlm.nih.gov/41875726/). *An Bras Dermatol*. [Review / Meta-Analysis]
Gómez Marín MDS (2026). [PMID: 41934467](https://pubmed.ncbi.nlm.nih.gov/41934467/). *Clin Exp Dermatol*. [Epidemiology / Natural History]
Zhao G (2026). [PMID: 41541192](https://pubmed.ncbi.nlm.nih.gov/41541192/). *Case Rep Dermatol*. [Case Report / Case Series]
Herrick AL (2026). [PMID: 41689194](https://pubmed.ncbi.nlm.nih.gov/41689194/). *Rheumatology (Oxford)*. [Review / Meta-Analysis]
Frazier W MD, MPH (2026). [PMID: 42101599](https://pubmed.ncbi.nlm.nih.gov/42101599/). *Am Fam Physician*. [Review / Meta-Analysis]
Vendhan S (2026). [PMID: 41313010](https://pubmed.ncbi.nlm.nih.gov/41313010/). *Int J Dermatol*. [Other]
AI-curated news mentioning livedoid vasculopathy
Updated May 18, 2026
A recent study identifies a combined phenotype of skeletal dysplasia and vasculopathy linked to an in-frame intragenic deletion in the PRKACA gene. This discovery enhances understanding of the genetic underpinnings of these rare conditions.