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A rare vaginal malformation characterized by the presence of a complete or incomplete septum dividing the vagina into two parallel cavities, resulting from failure of reabsorption of the midline uterine septum between the two fused Müllerian ducts during embryogenesis. Patients are often asymptomatic, but may present with menorrhagia, dysmenorrhea, dyspareunia, infertility, or spontaneous abortion. The condition may occur as an isolated malformation or in association with other Müllerian duct anomalies (such as septate uterus or uterus didelphys) or renal abnormalities.
Biomarker and diagnostic research for longitudinal vaginal septum has been reported in the published literature.
No clinical trials have been registered for longitudinal vaginal septum.
30 publications have been identified in PubMed for longitudinal vaginal septum. Research spans Case Report / Case Series (50%), Epidemiology / Natural History (17%), and Review / Meta-Analysis (10%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 15 | 50% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 1:00 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
5 |
17% |
Research summaries | 3 | 10% |
Laboratory research | 3 | 10% |
Clinical study results | 2 | 7% |
Testing and diagnosis research | 1 | 3% |
New treatment approaches | 1 | 3% |
Solomon AE (2026). [PMID: 42148713](https://pubmed.ncbi.nlm.nih.gov/42148713/). *Reprod Fertil*. [Basic Science / Preclinical]
Blanco-Breindel MF (2026). [PMID: 37603639](https://pubmed.ncbi.nlm.nih.gov/37603639/). *Unknown Journal*. [Review / Meta-Analysis]
Catena U (2026). [PMID: 41981807](https://pubmed.ncbi.nlm.nih.gov/41981807/). *Int J Gynaecol Obstet*. [Epidemiology / Natural History]
Wu YC (2026). [PMID: 41669329](https://pubmed.ncbi.nlm.nih.gov/41669329/). *Tzu Chi Med J*. [Review / Meta-Analysis]
Villamizar DM (2026). [PMID: 41779159](https://pubmed.ncbi.nlm.nih.gov/41779159/). *Pediatr Surg Int*. [Epidemiology / Natural History]
Su T (2026). [PMID: 42003911](https://pubmed.ncbi.nlm.nih.gov/42003911/). *Int J Biol Sci*. [Basic Science / Preclinical]
Soares CB (2026). [PMID: 41809419](https://pubmed.ncbi.nlm.nih.gov/41809419/). *Gynecol Oncol Rep*. [Case Report / Case Series]
AbouZeid AA (2026). [PMID: 40795933](https://pubmed.ncbi.nlm.nih.gov/40795933/). *Eur J Pediatr Surg*. [Clinical Trial Publication]
Ito M (2026). [PMID: 42231113](https://pubmed.ncbi.nlm.nih.gov/42231113/). *Asian J Endosc Surg*. [Case Report / Case Series]
Akcaoglu T (2025). [PMID: 40267823](https://pubmed.ncbi.nlm.nih.gov/40267823/). *Eur J Obstet Gynecol Reprod Biol*. [Review / Meta-Analysis]