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Lown-Ganong-Levine syndrome is an extremely rare conduction disorder characterized by a short PR interval (less than or equal to 120 ms) with normal QRS complex on electrocardiogram associated with the occurrence of episodes of atrial tachyarrythmias (e.g. atrial fibrillation, atrial tachycardia).
Features include: Permanent atrial fibrillation, Paroxysmal atrial tachycardia, Shortened PR interval, and Paroxysmal atrial fibrillation.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 3 | Permanent atrial fibrillation, Paroxysmal atrial tachycardia, Paroxysmal atrial fibrillation |
No clinical trials have been registered for Lown-Ganong-Levine syndrome.
2 publications have been identified in PubMed for Lown-Ganong-Levine syndrome. Research spans Other (50%) and Case Report / Case Series (50%).
Soos MP (2026). [PMID: 31536317](https://pubmed.ncbi.nlm.nih.gov/31536317/). *Unknown Journal*. [Other]
Srouji SM (2025). [PMID: 40352042](https://pubmed.ncbi.nlm.nih.gov/40352042/). *Cureus*. [Case Report / Case Series]
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 11:58 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Lown-Ganong-Levine syndrome