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Biomarker and diagnostic research for macrodactyly of toes has been reported in the published literature.
Estimated prevalence: 1-9 in 100,000 (Uncommon).
No clinical trials have been registered for macrodactyly of toes.
10 publications have been identified in PubMed for macrodactyly of toes. Research spans Review / Meta-Analysis (30%), Case Report / Case Series (30%), and Diagnostic / Biomarker (10%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 3 | 30% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:58 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
3 |
30% |
Testing and diagnosis research | 1 | 10% |
Clinical study results | 1 | 10% |
Disease patterns and progression | 1 | 10% |
New treatment approaches | 1 | 10% |
Van Carlen M (2026). [PMID: 41569133](https://pubmed.ncbi.nlm.nih.gov/41569133/). *Plastic and reconstructive surgery*. [Gene Therapy / Novel Therapeutics]
Miralles MJC (2025). [PMID: 41300579](https://pubmed.ncbi.nlm.nih.gov/41300579/). *Children (Basel, Switzerland)*. [Review / Meta-Analysis]
Tian MM (2025). [PMID: 40302584](https://pubmed.ncbi.nlm.nih.gov/40302584/). *Zhonghua bing li xue za zhi = Chinese journal of pathology*. [Diagnostic / Biomarker]
Liu Y (2025). [PMID: 40993711](https://pubmed.ncbi.nlm.nih.gov/40993711/). *Orphanet journal of rare diseases*. [Epidemiology / Natural History]
Li D (2025). [PMID: 41397800](https://pubmed.ncbi.nlm.nih.gov/41397800/). *Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery*. [Clinical Trial Publication]
Huang TC (2025). [PMID: 40689403](https://pubmed.ncbi.nlm.nih.gov/40689403/). *Journal of the American College of Emergency Physicians open*. [Review / Meta-Analysis]
Giżewska-Kacprzak K (2024). [PMID: 39062202](https://pubmed.ncbi.nlm.nih.gov/39062202/). *Children (Basel, Switzerland)*. [Review / Meta-Analysis]
Kilawa SI (2024). [PMID: 38692121](https://pubmed.ncbi.nlm.nih.gov/38692121/). *International journal of surgery case reports*. [Case Report / Case Series]
Russo AP (2024). [PMID: 39381491](https://pubmed.ncbi.nlm.nih.gov/39381491/). *Cureus*. [Case Report / Case Series]
Wang Y (2024). [PMID: 37832040](https://pubmed.ncbi.nlm.nih.gov/37832040/). *Plastic and reconstructive surgery*. [Case Report / Case Series]
AI-curated news mentioning macrodactyly of toes
Updated May 12, 2026
A recent study published in PubMed discusses the late-onset reactivation of hand macrodactyly in a septuagenarian. This research adds to the understanding of macrodactyly's progression and potential triggers in older populations.