Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Maculopapular cutaneous mastocytosis (MCM) is a form of cutaneous mastocytosis (CM) characterized by the presence of multiple hyperpigmented macules, papules or nodules associated with abnormal accumulation of mast cells in the skin.
Features include very common findings: Generalized abnormality of skin and Darier's sign; and common findings: Pruritus, Erythema, Macule, and Yellow papule. 21 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Skin | 6 | Generalized abnormality of skin, Pruritus, Erythema |
Biomarker and diagnostic research for maculopapular cutaneous mastocytosis has been reported in the published literature.
Phenotype severity distribution: 2 very common features, 4 common features.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for maculopapular cutaneous mastocytosis.
25 publications have been identified in PubMed for maculopapular cutaneous mastocytosis. Research spans Review / Meta-Analysis (28%), Case Report / Case Series (24%), and Epidemiology / Natural History (16%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 7 | 28% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:46 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
4 |
Vomiting, Diarrhea, Nausea |
Brain and nerves | 2 | Irritability, Headache |
Metabolism | 1 | Fever |
Bones and joints | 1 | Bone pain |
Lungs and breathing | 1 | Dyspnea |
Patient case studies
6 |
24% |
Disease patterns and progression | 4 | 16% |
Testing and diagnosis research | 3 | 12% |
Other research | 2 | 8% |
Laboratory research | 2 | 8% |
Clinical study results | 1 | 4% |
Kasmi D (2026). [PMID: 41836292](https://pubmed.ncbi.nlm.nih.gov/41836292/). *Front Cell Dev Biol*. [Basic Science / Preclinical]
Ahmed A (2026). [PMID: 30855840](https://pubmed.ncbi.nlm.nih.gov/30855840/). *Unknown Journal*. [Basic Science / Preclinical]
Alhajri A (2026). [PMID: 41971936](https://pubmed.ncbi.nlm.nih.gov/41971936/). *AME Case Rep*. [Case Report / Case Series]
Carter MC (2026). [PMID: 41285204](https://pubmed.ncbi.nlm.nih.gov/41285204/). *J Allergy Clin Immunol Pract*. [Review / Meta-Analysis]
King A (2026). [PMID: 40491135](https://pubmed.ncbi.nlm.nih.gov/40491135/). *J Cutan Med Surg*. [Other]
Macri A (2026). [PMID: 29494109](https://pubmed.ncbi.nlm.nih.gov/29494109/). *Unknown Journal*. [Case Report / Case Series]
Walker TD (2025). [PMID: 39887532](https://pubmed.ncbi.nlm.nih.gov/39887532/). *Pediatr Dermatol*. [Epidemiology / Natural History]
Franz T (2025). [PMID: 41136097](https://pubmed.ncbi.nlm.nih.gov/41136097/). *Immunol Allergy Clin North Am*. [Review / Meta-Analysis]
Liu X (2025). [PMID: 40860296](https://pubmed.ncbi.nlm.nih.gov/40860296/). *Clin Case Rep*. [Review / Meta-Analysis]
Rydz A (2025). [PMID: 39795638](https://pubmed.ncbi.nlm.nih.gov/39795638/). *Diagnostics (Basel)*. [Diagnostic / Biomarker]