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malignant adrenal gland pheochromocytoma - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

malignant adrenal gland pheochromocytoma

MONDO:0006288

Also known as:adrenal gland pheochromocytoma, malignantmalignant adrenal gland Chromaffinomamalignant adrenal gland chromaffin neoplasm

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Overview

A pheochromocytoma that metastasizes to other anatomic sites. Common sites of metastasis include lymph nodes, bones, liver, and lung. Morphologic features associated with malignant pheochromocytomas include: atypical mitotic figures, capsular and vascular invasion, tumor cell necrosis, and high mitotic activity.

Treatments1 FDA approved

Clinical Trials1 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for malignant adrenal gland pheochromocytoma has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for malignant adrenal gland pheochromocytoma, including METYROSINE (DEMSER, approved 1979).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.

243 publications have been identified in PubMed for malignant adrenal gland pheochromocytoma. Research spans Review / Meta-Analysis (32%), Clinical Trial Publication (17%), and Basic Science / Preclinical (16%).

Research Type	Count	% of Total
Research summaries	78

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 11:33 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→What are the benefits and potential side effects of DEMSER for managing malignant adrenal gland pheochromocytoma?
→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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malignant adrenal gland pheochromocytoma

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

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