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Malignant Sertoli-Leydig cell tumor of ovary is a rare malignant sex cord stromal tumor of ovary occurring typically in young women and characterized by manifestations of androgen excess (hirsutism, hair loss, amenorrhea, or oligomenorrhea), when functional.
2 clinical trials registered, 2 recruiting. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.
15 publications have been identified in PubMed for malignant Sertoli-Leydig cell tumor of ovary. Research spans Case Report / Case Series (40%), Epidemiology / Natural History (27%), and Basic Science / Preclinical (20%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 6 |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:38 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Disease patterns and progression | 4 | 27% |
Laboratory research | 3 | 20% |
Research summaries | 2 | 13% |
Arizpe D (2026). [PMID: 41905669](https://pubmed.ncbi.nlm.nih.gov/41905669/). *Human pathology*. [Case Report / Case Series]
Jie R (2026). [PMID: 41994298](https://pubmed.ncbi.nlm.nih.gov/41994298/). *Int J Womens Health*. [Case Report / Case Series]
Trecourt A (2026). [PMID: 41255082](https://pubmed.ncbi.nlm.nih.gov/41255082/). *The American journal of surgical pathology*. [Basic Science / Preclinical]
Li HC (2026). [PMID: 42036198](https://pubmed.ncbi.nlm.nih.gov/42036198/). *Taiwan J Obstet Gynecol*. [Case Report / Case Series]
Zou YS (2026). [PMID: 41395670](https://pubmed.ncbi.nlm.nih.gov/41395670/). *Histopathology*. [Basic Science / Preclinical]
Lin S (2025). [PMID: 40682079](https://pubmed.ncbi.nlm.nih.gov/40682079/). *BMC women's health*. [Case Report / Case Series]
Nelson AT (2025). [PMID: 40267387](https://pubmed.ncbi.nlm.nih.gov/40267387/). *JCO precision oncology*. [Epidemiology / Natural History]
Karstensen S (2025). [PMID: 39848393](https://pubmed.ncbi.nlm.nih.gov/39848393/). *American journal of obstetrics and gynecology*. [Epidemiology / Natural History]
Němejcová K (2025). [PMID: 39592485](https://pubmed.ncbi.nlm.nih.gov/39592485/). *Virchows Archiv : an international journal of pathology*. [Basic Science / Preclinical]
Bozhuyuk Sahin T (2025). [PMID: 41312051](https://pubmed.ncbi.nlm.nih.gov/41312051/). *Case reports in oncological medicine*. [Case Report / Case Series]