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A Leydig cell tumor characterized by a large size, cellular atypia, high mitotic activity, vascular invasion and necrotic changes. The prognosis is usually poor.
Biomarker and diagnostic research for malignant testicular Leydig cell tumor has been reported in the published literature.
1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy, procedural interventions, and biologic therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.
63 publications have been identified in PubMed for malignant testicular Leydig cell tumor. Research spans Case Report / Case Series (35%), Basic Science / Preclinical (27%), and Diagnostic / Biomarker (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 22 |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:03 PM UTC
Laboratory research | 17 | 27% |
Testing and diagnosis research | 9 | 14% |
Research summaries | 8 | 13% |
Clinical study results | 4 | 6% |
Disease patterns and progression | 3 | 5% |
Shiobara K (2026). [PMID: 42062885](https://pubmed.ncbi.nlm.nih.gov/42062885/). *Hinyokika Kiyo*. [Case Report / Case Series]
Lobo J (2026). [PMID: 41384702](https://pubmed.ncbi.nlm.nih.gov/41384702/). *Histopathology*. [Review / Meta-Analysis]
Mura MD (2026). [PMID: 41671911](https://pubmed.ncbi.nlm.nih.gov/41671911/). *Annals of diagnostic pathology*. [Diagnostic / Biomarker]
Lobo J (2026). [PMID: 41152570](https://pubmed.ncbi.nlm.nih.gov/41152570/). *The Journal of pathology*. [Basic Science / Preclinical]
Abe T (2026). [PMID: 41808310](https://pubmed.ncbi.nlm.nih.gov/41808310/). *International journal of urology : official journal of the Japanese Urological Association*. [Clinical Trial Publication]
Yazıcı MC (2026). [PMID: 41778968](https://pubmed.ncbi.nlm.nih.gov/41778968/). *Fetal and pediatric pathology*. [Diagnostic / Biomarker]
Alfano M (2026). [PMID: 40658795](https://pubmed.ncbi.nlm.nih.gov/40658795/). *The Journal of clinical endocrinology and metabolism*. [Basic Science / Preclinical]
Zhao J (2026). [PMID: 41443279](https://pubmed.ncbi.nlm.nih.gov/41443279/). *Human pathology*. [Basic Science / Preclinical]
Choudhry MFK (2026). [PMID: 41064901](https://pubmed.ncbi.nlm.nih.gov/41064901/). *Histopathology*. [Basic Science / Preclinical]
Choiniere R (2026). [PMID: 41263775](https://pubmed.ncbi.nlm.nih.gov/41263775/). *Histopathology*. [Basic Science / Preclinical]