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A congenital or acquired developmental disorder in which the circumference of the head is smaller than normal for the person's age and sex.
Biomarker and diagnostic research for microcephaly has been reported in the published literature.
4 clinical trials registered, 3 recruiting. Interventions under study include other interventions and biologic therapy. Pipeline includes 1 PHASE1. Research is sponsored by a mix of industry and academic institutions.
330 publications have been identified in PubMed for microcephaly. Research spans Basic Science / Preclinical (39%), Case Report / Case Series (24%), and Review / Meta-Analysis (17%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 128 |
Data assembled from 3 of 12 sources · Last updated Oct 2, 2026, 11:47 PM UTC
Patient case studies | 78 | 24% |
Research summaries | 57 | 17% |
Disease patterns and progression | 44 | 13% |
Testing and diagnosis research | 10 | 3% |
New treatment approaches | 7 | 2% |
Clinical study results | 4 | 1% |
Other research | 2 | 1% |
Gowda VK (2026). [PMID: 41603106](https://pubmed.ncbi.nlm.nih.gov/41603106/). *Am J Med Genet A*. [Case Report / Case Series]
Tibbe D (2026). [PMID: 41962535](https://pubmed.ncbi.nlm.nih.gov/41962535/). *Am J Hum Genet*. [Basic Science / Preclinical]
Hwang S (2026). [PMID: 41152456](https://pubmed.ncbi.nlm.nih.gov/41152456/). *J Hum Genet*. [Epidemiology / Natural History]
Tüysüz B (2026). [PMID: 42141383](https://pubmed.ncbi.nlm.nih.gov/42141383/). *Clin Genet*. [Epidemiology / Natural History]
Rotulo GA (2026). [PMID: 41390316](https://pubmed.ncbi.nlm.nih.gov/41390316/). *Pediatr Neonatol*. [Review / Meta-Analysis]
da Silva Pone MV (2026). [PMID: 41600844](https://pubmed.ncbi.nlm.nih.gov/41600844/). *Viruses*. [Other]
Sudnawa KK (2026). [PMID: 40734308](https://pubmed.ncbi.nlm.nih.gov/40734308/). *Clin Genet*. [Epidemiology / Natural History]
Yuan L (2026). [PMID: 41507200](https://pubmed.ncbi.nlm.nih.gov/41507200/). *Nature communications*. [Basic Science / Preclinical]
Mangla M (2026). [PMID: 40878775](https://pubmed.ncbi.nlm.nih.gov/40878775/). *J Neonatal Perinatal Med*. [Review / Meta-Analysis]
Ogmen K (2026). [PMID: 41427784](https://pubmed.ncbi.nlm.nih.gov/41427784/). *JCI Insight*. [Epidemiology / Natural History]
AI-curated news mentioning microcephaly
Updated Mar 2, 2026
Research identifies bi-allelic GSPT1 variants linked to a syndromic neurodevelopmental disorder, which includes symptoms of intellectual disability and microcephaly. This discovery enhances understanding of genetic factors in rare neurodevelopmental conditions.
Children born with microcephaly due to congenital Zika virus infection encounter significant health and developmental challenges by 19-24 months of age. This highlights the ongoing need for support and resources for affected families.
CDC allocates nearly $184 million to combat Zika virus and its associated health risks, including microcephaly. This funding will support various states, territories, and universities in their efforts to protect public health.
A study reveals a four-fold increase in microcephaly cases in Colombia following the 2016 Zika virus outbreak, indicating that the risk is highest among pregnant women infected early in their pregnancy. This finding underscores the broader impact of Zika virus outbreaks beyond Brazil.