Nance-Horan syndrome

Nance-Horan syndrome is a rare genetic condition that mainly affects males. It is known for causing congenital cataracts (present at birth), small eyes (microcornea), dental irregularities, and distinctive facial features. These features together create a recognizable pattern that helps in understanding the condition. People with this condition typically experience vision issues from birth due to the presence of cataracts, along with an unusual appearance of the eyes, teeth, and face. The syndrome is noted in medical literature and is associated with specific gene changes that play a role in its development.

Common signs of Nance-Horan syndrome include congenital cataracts, which affect vision from birth, small eyes (microcornea), dental anomalies, and facial dysmorphism. These symptoms create a distinct pattern that is often noted by healthcare providers when assessing individuals with this condition.

Nance-Horan syndrome is caused by changes in the NHS gene. The syndrome follows an X-linked dominant pattern, meaning it is usually seen in males while females may be less severely affected or may show minimal symptoms. This genetic factor is central to the condition’s development.

Information about treatment is currently limited for this condition.

Information about prognosis is currently limited for this condition.

Information about research is currently limited for this condition.