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Nasopharyngeal carcinoma is defined in the packet as a carcinoma arising from the nasopharyngeal epithelium. The definition lists keratinizing squamous cell carcinoma, nonkeratinizing carcinoma (differentiated and undifferentiated), basaloid squamous cell carcinoma, and papillary adenocarcinoma as included types. The packet lists no associated genes, and prevalence and age of onset are not certified in this packet. Reference identifiers include Orphanet:150 and GARD:7163. Listed subtypes include carcinoma in situ of nasopharynx and undifferentiated carcinoma of nasopharynx.
Symptoms, characteristic findings, and age of onset are not certified in this packet, so no clinical features are described here.
The packet lists no associated genes and no inheritance patterns, so the genetic basis and any pattern of inheritance are not certified in this packet.
Diagnostic methods and criteria are not certified in this packet. One listed clinical trial, NCT02063399, is titled as a prospective nasopharyngeal carcinoma screening study using plasma Epstein-Barr virus DNA analysis; the trial title alone does not establish a diagnostic approach.
According to the packet's approved-treatment records, LOQTORZI (toripalimab-tpzi), a BLA product, received FDA approval on 2023-10-27 and has an ACTIVE market status. The packet's orphan-drug listing associates Loqtorzi with the indication of treatment of nasopharyngeal carcinoma. The packet's orphan-drug listing also includes several products with DESIGNATED status for nasopharyngeal carcinoma, including pembrolizumab, tislelizumab, and nanatinostat with valganciclovir; orphan designation is not FDA approval. The packet certifies no foundational or supportive therapies and no stage-specific treatment information.
293 trials found
Prognosis and natural history are not certified in this packet.
According to ClinicalTrials.gov records summarized in the packet, numerous active studies are associated with this condition. Examples with nasopharyngeal carcinoma in the title include NCT06029270, a Phase 2 study sponsored by the National Cancer Institute that adds relatlimab to immunotherapy in recurrent or metastatic nasopharyngeal cancer (recruiting; 2024-07-15 to 2029-04-30); NCT04875611, a Phase 2 nivolumab study sponsored by the Maria Sklodowska-Curie National Research Institute of Oncology (recruiting; 2021-08-26 to 2027-12-31); and NCT06064097, a Phase 2 study of nivolumab with chemotherapy drugs sponsored by the National Cancer Institute (recruiting; 2024-06-25 to 2027-03-31). A search link for ClinicalTrials.gov is included in the packet. Trial titles do not establish the effect of any intervention.
Data assembled from 5 of 12 sources · Last updated Nov 4, 2026, 3:00 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
AI-curated news mentioning nasopharyngeal carcinoma
Updated Oct 16, 2026
A recent study analyzes the burden of nasopharyngeal carcinoma from 1990 to 2023, projecting mortality trends up to 2050. This research highlights the ongoing challenges in managing this rare cancer globally.
A case report details the development of radiation-induced second primary gingival squamous cell carcinoma occurring 26 years post-radiotherapy for nasopharyngeal carcinoma. This highlights potential long-term risks associated with radiation treatment.
A rare case report details primary Klebsiella pneumoniae ventriculitis in a patient with nasopharyngeal carcinoma following radiotherapy. This finding highlights potential complications in cancer treatment, emphasizing the need for vigilance in monitoring patients.