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Nephrogenic systemic fibrosis (NSF) is a rare systemic fibrosing condition observed in renally impaired patients and characterized by a hardening and thickening of the skin with fibrotic plaques or papules, pruritus, joint pain and stiffness, muscle weakness, limitation of range of motion, and yellowed eyes. It is generally associated with administration of gadolinium-based magnetic resonance imaging contrast agents (GBCA) in patients with kidney disease.
Biomarker and diagnostic research for nephrogenic systemic fibrosis has been reported in the published literature.
No clinical trials have been registered for nephrogenic systemic fibrosis.
45 publications have been identified in PubMed for nephrogenic systemic fibrosis. Research spans Review / Meta-Analysis (55%), Basic Science / Preclinical (14%), and Other (7%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 23 | 55% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 3:26 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
6 |
14% |
Other research | 3 | 7% |
Patient case studies | 3 | 7% |
Testing and diagnosis research | 2 | 5% |
Disease patterns and progression | 2 | 5% |
New treatment approaches | 2 | 5% |
Clinical study results | 1 | 2% |
Mitin D (2026). [PMID: 41900043](https://pubmed.ncbi.nlm.nih.gov/41900043/). *Molecules*. [Review / Meta-Analysis]
El Sayed T (2026). [PMID: 42269372](https://pubmed.ncbi.nlm.nih.gov/42269372/). *J Inorg Biochem*. [Basic Science / Preclinical]
Kim JW (2026). [PMID: 41681769](https://pubmed.ncbi.nlm.nih.gov/41681769/). *Diagnostics (Basel)*. [Epidemiology / Natural History]
Verhellen C (2026). [PMID: 41805283](https://pubmed.ncbi.nlm.nih.gov/41805283/). *Nephrol Ther*. [Review / Meta-Analysis]
Shamam YM (2026). [PMID: 33620831](https://pubmed.ncbi.nlm.nih.gov/33620831/). *Unknown Journal*. [Other]
Wang KC (2026). [PMID: 39870554](https://pubmed.ncbi.nlm.nih.gov/39870554/). *J Formos Med Assoc*. [Review / Meta-Analysis]
Wagner B (2026). [PMID: 41548700](https://pubmed.ncbi.nlm.nih.gov/41548700/). *Magn Reson Imaging*. [Other]
Long MR (2026). [PMID: 41152142](https://pubmed.ncbi.nlm.nih.gov/41152142/). *Magn Reson Med*. [Review / Meta-Analysis]
Eidex Z (2026). [PMID: 41604705](https://pubmed.ncbi.nlm.nih.gov/41604705/). *Biomed Phys Eng Express*. [Basic Science / Preclinical]
Kwek XYR (2026). [PMID: 41234052](https://pubmed.ncbi.nlm.nih.gov/41234052/). *QJM*. [Case Report / Case Series]
AI-curated news mentioning nephrogenic systemic fibrosis
Updated May 27, 2026
A multisociety consensus statement has established a new common definition and diagnostic criteria for primary systemic vasculitis disease (PSVD) and nephrogenic systemic fibrosis (NSF). This initiative aims to standardize diagnosis and improve patient outcomes.