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A subtype of classical Hodgkin lymphoma characterized by collagen bands that surround at least one nodule, and Hodgkin and Reed-Sternberg cells with lacunar type morphology. (WHO, 2008)
2 clinical trials registered. Interventions under study include drug therapy, other interventions, biologic therapy, and procedural interventions. Pipeline includes 1 PHASE3, 1 PHASE2. Research is primarily sponsored by academic and government institutions.
7 publications have been identified in PubMed for nodular sclerosis classical Hodgkin lymphoma. Research spans Case Report / Case Series (33%), Basic Science / Preclinical (33%), and Review / Meta-Analysis (17%).
Xiao X (2026). [PMID: 41692398](https://pubmed.ncbi.nlm.nih.gov/41692398/). *Laboratory investigation; a journal of technical methods and pathology*. [Basic Science / Preclinical]
Diederich VJ (2026). [PMID: 41406636](https://pubmed.ncbi.nlm.nih.gov/41406636/). *Acta histochemica*. [Basic Science / Preclinical]
Tolou-Ghamari Z (2026). [PMID: 40692149](https://pubmed.ncbi.nlm.nih.gov/40692149/). *Current cardiology reviews*. [Epidemiology / Natural History]
Attieh M (2025). [PMID: 41439210](https://pubmed.ncbi.nlm.nih.gov/41439210/). *Case reports in hematology*. [Case Report / Case Series]
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 4:31 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Chua NA (2024). [PMID: 39663134](https://pubmed.ncbi.nlm.nih.gov/39663134/). *BMJ case reports*. [Case Report / Case Series]
Mogensen N (2024). [PMID: 38596833](https://pubmed.ncbi.nlm.nih.gov/38596833/). *Acta paediatrica (Oslo, Norway : 1992)*. [Review / Meta-Analysis]
AI-curated news mentioning nodular sclerosis classical Hodgkin lymphoma
Updated May 24, 2026
A recent SEER analysis provides insights into the clinical features and prognostic factors of lymphocyte-depleted classical Hodgkin lymphoma. This population-based study enhances understanding of outcomes in this rare subtype of Hodgkin lymphoma.