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Non-hypoproteinemic hypertrophic gastropathy is a rare gastroesophageal disease characterized by diffusely enlarged gastric folds, excessive mucus secretion, normal serum protein and gastric TGF-alpha levels. Patients typically present anemia, abdominal pain not related to eating or bowel habits and absence of peripheral edema.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for non-hypoproteinemic hypertrophic gastropathy.
2 publications have been identified in PubMed for non-hypoproteinemic hypertrophic gastropathy. Research spans Case Report / Case Series (100%).
Wang L (2025). [PMID: 41041446](https://pubmed.ncbi.nlm.nih.gov/41041446/). *Front Med (Lausanne)*. [Case Report / Case Series]
Wu J (2025). [PMID: 40887784](https://pubmed.ncbi.nlm.nih.gov/40887784/). *Am J Case Rep*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 6:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
AI-curated news mentioning non-hypoproteinemic hypertrophic gastropathy
Updated Mar 2, 2026
A case study highlights a gastric neuroendocrine tumor exhibiting a unique raspberry-like appearance, potentially linked to acid-suppressive therapy-related gastropathy. This finding may provide insights into the pathology of gastric tumors in patients undergoing long-term acid suppression.