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Swelling of the optic disk, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause optic atrophy and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
2 clinical trials registered. Interventions under study include other interventions. Pipeline includes 1 EARLY_PHASE1. Research is primarily sponsored by academic and government institutions.
9 publications have been identified in PubMed for optic papillitis. Research spans Case Report / Case Series (38%), Review / Meta-Analysis (25%), and Epidemiology / Natural History (25%).
Cuzzubbo S (2026). [PMID: 41759413](https://pubmed.ncbi.nlm.nih.gov/41759413/). *European journal of cancer (Oxford, England : 1990)*. [Case Report / Case Series]
Wang MN (2025). [PMID: 39449345](https://pubmed.ncbi.nlm.nih.gov/39449345/). *Current molecular medicine*. [Review / Meta-Analysis]
Murty T (2025). [PMID: 40726603](https://pubmed.ncbi.nlm.nih.gov/40726603/). *Ocular oncology and pathology*. [Basic Science / Preclinical]
Abbass NJ (2025). [PMID: 40011738](https://pubmed.ncbi.nlm.nih.gov/40011738/). *Eye (London, England)*. [Epidemiology / Natural History]
Zaman M (2025). [PMID: 41109329](https://pubmed.ncbi.nlm.nih.gov/41109329/). *Canadian journal of ophthalmology. Journal canadien d'ophtalmologie*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 1:47 AM UTC
Garulo Nicolás J (2025). [PMID: 40692011](https://pubmed.ncbi.nlm.nih.gov/40692011/). *Archivos de la Sociedad Espanola de Oftalmologia*. [Case Report / Case Series]
Nonaka K (2024). [PMID: 39606524](https://pubmed.ncbi.nlm.nih.gov/39606524/). *Cureus*. [Case Report / Case Series]
Li XJ (2024). [PMID: 38988718](https://pubmed.ncbi.nlm.nih.gov/38988718/). *ACG case reports journal*. [Epidemiology / Natural History]